CFB Game Prediction

Missouri vs Louisiana-Lafayette Prediction & Betting Tips for CFB Week 3 on 9/13/2025

Want our best Missouri vs Louisiana-Lafayette prediction for 9/13/25? Get our College Football betting tip as the Louisiana-Lafayette travel to Missouri in Week 3 on 9/13/25 at Faurot Field at Memorial Stadium, in Missouri. Knup Sports has your free CFB pick!

As Week 3 of the 2025 college football season unfolds, the Louisiana-Lafayette Ragin’ Cajuns will travel to Columbia, Missouri to take on the Missouri Tigers. The game is set to take place at Faurot Field at Memorial Stadium on Saturday, September 13, 2025, with kickoff scheduled for 4:00 PM. Fans can catch the action on the SEC Network.

Louisiana-Lafayette enters this matchup with a 1-1 record, having recently secured a 34-10 win against McNeese State. Their season opener, however, resulted in a narrow 14-12 loss to Rice. This game marks the Ragin’ Cajuns’ first road game of the season, as they look to improve on their performance.

On the other side, the Missouri Tigers hold a 2-0 record, highlighted by decisive victories over Kansas and Central Arkansas. Ranked #25 in the AP Poll, Missouri will be aiming to maintain their perfect home record. Their recent performance against Kansas saw them emerge with a 42-31 victory, showcasing their offensive capabilities.

Missouri vs Louisiana-Lafayette At a Glance

  • Game Location: Faurot Field at Memorial Stadium in Columbia, MO
  • Kickoff Time: Saturday, September 13, 2025, at 4:00 PM
  • Broadcast: SEC Network
  • Missouri Tigers Current Record: 2-0
  • Louisiana-Lafayette Ragin’ Cajuns Current Record: 1-1
  • Betting Odds: Missouri favored with a -27.0 spread

Missouri Tigers Roar into Week 3 Against the Ragin’ Cajuns

Offensive Insights

The Missouri Tigers have started their 2025 season with a potent offense, scoring 103 points, ranking 7th in the nation. Their aerial attack is noteworthy, amassing 675 passing yards, placing them at 15th overall. On the ground, they have been effective as well, with 482 rushing yards, ranking 22nd.

Beau Pribula has been instrumental at quarterback, leading the Tigers with 617 passing yards and 5 touchdowns. His contribution is a significant factor in Missouri’s success, ranking him first in passing yards and touchdowns for the team. Ahmad Hardy also deserves mention, rushing for 212 yards, making him the leading running back for Missouri.

Defensive Dynamics

Missouri’s defense has proven to be a strong unit, giving up only 37 points, which places them 28th nationally. They are aggressive in creating turnovers, with 2 interceptions ranking them 3rd in the nation. Their pass rush has been effective, achieving 5 sacks, ranking 6th.

The defensive line’s ability to pressure quarterbacks is a strength, contributing to their high sack count. This pressure has allowed the secondary to capitalize, securing interceptions at crucial moments. Fumble recoveries have also been part of their strategy, with 1 recovery ranking them 5th.

Player Spotlight

Kevin Coleman Jr. has been a standout receiver, with 16 receptions and 174 receiving yards, ranking him 1st for the Tigers. His ability to make big plays has been a key element of the Tigers’ passing attack. Brett Norfleet, a tight end, has also been effective with 3 receiving touchdowns.

On special teams, Robert Meyer has been reliable, with 2 field goals and 8 extra points. His contributions have been vital in maintaining Missouri’s scoring momentum. The absence of kicker Blake Craig due to injury means Meyer will play an even more critical role moving forward.

Betting Trends

  • SU All Games: 2-0 (100.0%)
  • SU as Favorite: 2-0 (100.0%)
  • SU in Home Games: 2-0 (100.0%)
  • ATS All Games: 2-0 (100.0%)
  • ATS as Favorite: 2-0 (100.0%)
  • O/U All Games: 2-0 (100.0%)
  • O/U Totals ≥ 50: 2-0 (100.0%)

The Ragin’ Cajuns Roll into Missouri: A Closer Look at Louisiana-Lafayette’s Next Game

Offensive Performance Analysis

The Louisiana-Lafayette Ragin’ Cajuns’ offense has shown mixed results this season. With an average of 46 points for, they rank 47th nationally, indicating a capable offense. However, their passing game lags significantly, positioned at 137th with only 174 passing yards.

The ground game is the cornerstone of their offensive attack. Ranking 25th with 466 rushing yards, the Ragin’ Cajuns rely heavily on their running backs to move the chains. This is further evidenced by their 23rd rank in first downs, with a total of 41.

Defensive Strengths

Defensively, the Ragin’ Cajuns have been impressive, allowing only 24 points against, which ranks them 16th nationally. Their defensive line has been effective, registering 3 sacks and earning an 8th place ranking. Additionally, they have demonstrated an opportunistic defense with 1 interception and 1 fumble recovery, both ranking in the top 5.

This ability to create turnovers will be crucial as they head into their next game against the Missouri Tigers. Maintaining this defensive momentum will be key to countering Missouri’s offense.

Key Players to Watch

Despite his injury, quarterback Walker Howard was off to a promising start with 88 passing yards in his single appearance. In his absence, Daniel Beale has taken the reins, contributing 86 passing yards and 1 touchdown across two games. Beale’s performance will be vital in the upcoming matchups.

The rushing attack is led by Bill Davis, who has amassed 190 rushing yards and 2 touchdowns in two games, placing him 31st nationally in rushing yards. His ability to break through defenses will be a focal point for the Ragin’ Cajuns’ offense.

Betting Trends

  • SU All Games: 1-1 (50.0%)
  • ATS All Games: 2-0 (100.0%)
  • O/U All Games: 0-2 (0.0%)
  • SU as Favorite: 1-1 (50.0%)
  • ATS as Favorite: 2-0 (100.0%)
  • O/U as Favorite: 0-2 (0.0%)
  • SU After a Win: 0-1 (0.0%)

Louisiana-Lafayette has shown strength against the spread, going 2-0, but their games have consistently gone under, with a 0-2 record. Bettors should consider these trends when wagering on their upcoming games.

Missouri vs Louisiana-Lafayette Prediction: Over 49.0

Missouri Tigers have been performing impressively this season, scoring a total of 103 points over their first two games, which ranks them 7th in points for the 2025 season. Their offensive prowess is complemented by strong passing and rushing yards, indicating a potent attack that can exploit the Louisiana-Lafayette defense. This offensive strength suggests that Missouri could score heavily once again.

Louisiana-Lafayette, on the other hand, has a strong rushing game, currently ranking 25th in rushing yards. This could help them control the game clock and score, even if not at the level of Missouri. Despite their previous loss to TCU with only three points, their offensive capabilities should not be underestimated.

The current game total is set at 49.0, and Missouri’s recent games have consistently exceeded this mark. Given Missouri’s high-scoring potential and the ability of Louisiana-Lafayette to contribute points, the over on this line seems favorable.

Considering the offensive statistics from both teams, a projected score of Missouri 38 – Louisiana-Lafayette 17 aligns with the expectation that the combined score will exceed the over/under line. Thus, the over 49.0 is the recommended pick for this game.

  • Missouri vs Louisiana-Lafayette Prediction: Over 49.0
  • Missouri vs Louisiana-Lafayette Score: Missouri 38 – Louisiana-Lafayette 17
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