CFB Game Prediction

LSU vs South Carolina Prediction & Betting Tips for CFB Week 7 on 10/11/2025

Want our best LSU vs South Carolina prediction for 10/11/25? Get our College Football betting tip as the South Carolina travel to LSU in Week 7 on 10/11/25 at Tiger Stadium (LA), in LSU. Knup Sports has your free CFB pick!

In Week 7 of the 2025 college football season, the South Carolina Gamecocks will travel to Baton Rouge to take on the LSU Tigers at Tiger Stadium. The game is scheduled for a nighttime kickoff at 7:45 PM ET and will be broadcast on SECN. Both teams, part of the Southeastern Conference, are looking to gain momentum as the season progresses.

The South Carolina Gamecocks come into this game with a 3-2 record, having recently defeated the Kentucky Wildcats 35-13 at home. They stand at 1-2 in conference play and have shown mixed results on the road with a 1-1 record. Their last postseason appearance was in the Cheez-It Citrus Bowl, where they fell to the Illinois Fighting Illini.

On the other hand, the LSU Tigers hold a 4-1 record and have been perfect at home with a 3-0 mark. Ranked #11 in both the AP and Coaches Polls, LSU looks to bounce back from a narrow 24-19 loss to Ole Miss. Their recent success in the Kinder’s Texas Bowl, where they defeated Baylor, underscores their capability in high-stakes games.

LSU vs South Carolina At a Glance

  • Game Date and Time: Saturday, October 11, 2025 at 7:45 PM
  • Venue: Tiger Stadium (LA) in Baton Rouge, LA
  • TV Channel: SECN
  • South Carolina Record: 3-2 for the season
  • LSU Record: 4-1 for the season
  • Game Odds: LSU favored with a -345 moneyline and an 8.5-point spread

LSU Tigers Set for a Fierce Battle Against South Carolina

Offensive Overview

South Carolina has shown some promising signs on offense this season, ranking 51st in passing yards with a total of 1295 yards. However, their rushing attack has struggled, ranking 113th with just 535 rushing yards. Their offensive strategy may rely heavily on the passing game to challenge LSU’s defense.

Despite ranking 62nd in points scored this season, South Carolina’s offense has managed to accumulate 110 first downs, placing them 33rd in this category. This indicates a capability to sustain drives, though they will need to convert these opportunities into points against a strong LSU defense.

Defensive Strengths

Defensively, South Carolina has been resilient, ranking 27th in points allowed with only 61 points against them this season. They have demonstrated an ability to pressure quarterbacks, ranking 13th in sacks with 11 so far. This defensive front will be crucial in disrupting LSU’s offensive rhythm.

South Carolina’s secondary has also been impressive, intercepting the ball 7 times and ranking 8th in the nation. Their ability to create turnovers could be a key factor in stifling LSU’s passing attack, especially if they can capitalize on these opportunities.

Recent Performance

In their recent game against Ole Miss, South Carolina’s defense faced challenges, allowing 314 passing yards and 170 rushing yards in a 24-19 loss. Despite the defensive struggles, they managed to keep the game competitive until the end.

Their offense, however, had difficulties moving the chains, achieving only 16 first downs compared to Ole Miss’s 28. This game highlighted the need for South Carolina to find more consistency on both sides of the ball to compete at a high level.

Team Betting Trends

  • ATS – Away Games: South Carolina has covered the spread in 6 of their last 8 away games (75%).
  • O/U – Against SEC Teams: The total has gone over in 5 of their last 7 games against SEC opponents (71.4%).
  • SU – Following a Loss: South Carolina has won 4 of their last 6 games after a loss (66.7%).

With a mix of promising defensive capabilities and a passing game that can exploit weaknesses, South Carolina will need to focus on executing both offensively and defensively to challenge LSU. This matchup will test their resilience against a formidable opponent, and adjustments will be key to their success.

South Carolina Gamecocks Look to Continue Strong Start in Upcoming Game

Offensive Overview

The South Carolina Gamecocks have had a mixed start to their 2025 season on the offensive front. They currently rank 67th in points scored with 124 points, showcasing a need for improvement compared to their 38th ranking last year.

In terms of passing yards, the Gamecocks have accumulated 1056 yards, placing them 88th nationally, which is a step down from their 64th rank last season. Their rushing attack has been less effective, ranking 115th with only 506 yards.

Defensive Strengths

Defensively, South Carolina has been a formidable force, allowing only 94 points against them, earning them the 48th spot in points allowed. The Gamecocks have been aggressive in their pass rush, securing 15 sacks and ranking 9th nationally.

Their secondary has been exceptional, with 4 interceptions ranking them 5th, and their ability to recover 3 fumbles places them at 6th nationally. This defensive prowess has been a key factor in their performances this season.

Recent Performance

In their latest game, South Carolina dominated Kentucky with a 35-13 victory at home. This win was fueled by a balanced attack, as they managed to amass 163 passing yards and 178 rushing yards.

However, they encountered difficulties in their previous outing against Missouri, where they were outmatched in a 29-20 loss. This game exposed vulnerabilities in their rushing defense, as they allowed 287 rushing yards.

Key Players

Quarterback LaNorris Sellers has been a pivotal figure for the Gamecocks, throwing for 886 yards over five games, ranking him 96th in the nation. His leadership will be crucial for South Carolina’s success moving forward.

Rahsul Faison, the team’s leading rusher, has accumulated 163 rushing yards. His contributions, along with those of wide receiver Vandrevius Jacobs, who leads the team with 323 receiving yards, will be vital against their upcoming opponents.

Injury Report

South Carolina is dealing with a few injury concerns ahead of their next game. Notable players such as Buddy Mack III, Cason Henry, and Nolan Hay are questionable with undisclosed injuries.

Defensive lineman Gabriel Brownlow-Dindy, though dealing with an injury, is expected to play, which could provide a boost to their defensive line.

Upcoming Game Analysis

The Gamecocks are preparing for a challenging game against the LSU Tigers at Tiger Stadium. Currently listed as 9.5-point underdogs, South Carolina will need to rely on their strong defensive capabilities to keep the game competitive.

With a total set at 43.5 points, both teams will likely focus on controlling the pace and minimizing mistakes to gain an advantage in this pivotal game.

Team Betting Trends

  • ATS – Away Games: Last 8 Games (2023–2025) → 8-0 (100.0%)
  • ATS – After Loss: Last 5 Games (2024–2025) → 5-0 (100.0%)
  • O/U – After Loss: Last 5 Games (2024–2025) → 5-0 (100.0%)
  • ATS – As Underdog: Last 4 Games (2024–2025) → 4-0 (100.0%)

LSU vs South Carolina Prediction: LSU -8.5

LSU enters this game with an impressive 4-1 record, ranking #11 in both the AP and Coaches Polls. The Tigers are particularly strong at home, boasting an undefeated 3-0 record in Baton Rouge this season. Their ability to perform well on their home turf makes them a favorable option to cover the -8.5 spread.

South Carolina, with a 3-2 record, has been inconsistent, especially in conference play where they stand at 1-2. The Gamecocks’ road record is balanced at 1-1, but they may struggle against a top-ranked team like LSU. Considering their offensive ranking and road performance, they might find it challenging to keep pace with the Tigers.

LSU’s offense has shown prowess in both passing and rushing, ranking 51st and 113rd respectively. Combined with a strong home game track record (24-2 in their last 26 games), LSU has the tools to dominate the Gamecocks defensively and offensively, covering the spread comfortably.

Expect LSU to capitalize on their superior defense, which has only allowed 61 points against them this season, ranking 27th in the nation. This advantage, along with their offensive capabilities, should enable them to win decisively, covering the -8.5 spread.

  • LSU vs South Carolina Prediction: LSU -8.5
  • LSU vs South Carolina Score: LSU 34 – South Carolina 17
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