NFL Game Prediction

Giants vs Eagles Prediction & Betting Tips for NFL Week 6 on 10/9/2025

Want our best Giants vs Eagles prediction for NFL week 6 on 10/9/25? Get our NFL betting tip as the Philadelphia Eagles travel to the New York Giants on 10/9/25 at MetLife Stadium, in New York. Knup Sports has your free pick!

The Philadelphia Eagles travel to MetLife Stadium in East Rutherford, NJ, for a Thursday night game against the New York Giants in Week 6 of the 2025 NFL season. The Eagles, with a strong 4-1 record, are looking to bounce back after a narrow 21-17 loss to the Denver Broncos. With a perfect road record so far, Head Coach Nick Sirianni and his team are set to face their NFC East rivals under clear skies and a mild breeze.

Meanwhile, the New York Giants, led by Head Coach Brian Daboll, aim to improve their standing with a current 1-4 record. Despite the challenging start to the season, the Giants secured a win at home against the Los Angeles Chargers in Week 4, showcasing their potential to perform well at MetLife Stadium. The Giants’ recent loss to the New Orleans Saints further fuels their need to capitalize on home-field advantage.

This NFC East matchup will be broadcast on AMZN, with the Eagles favored at a moneyline of -384 and a spread of -7.5. The Giants, who have struggled with turnovers, are tasked with overcoming their underdog status against a Philadelphia team that has demonstrated resilience on the road. With both teams eager to establish dominance in their division, this game promises to offer an exciting evening of football.

Giants vs Eagles At a Glance

  • Game Date: Thursday, October 9, 2025 at 8:15 PM (Night Game)
  • Location: MetLife Stadium in East Rutherford, NJ, USA — Outdoor Field
  • Weather Forecast: Mild day with a light breeze, ‘Clear Sky’ conditions
  • TV Channel: AMZN
  • Philadelphia Eagles Record: 4-1-0 this season, with a 2-0-0 road record
  • New York Giants Record: 1-4-0 this season, with a 1-1-0 home record

Giants Seek Redemption Against the Eagles

Team Overview

The New York Giants are heading into Week 6 with a 1-4 record, having faced a tough schedule so far. Their offensive struggles are apparent, ranking 29th in scoring with just 273 points accumulated in the 2024 regular season. The Giants have also struggled to move the ball through the air, ranking 28th in passing yards.

Defensively, the Giants have been inconsistent, allowing 415 points, placing them 20th in opponent scoring. Despite this, their pass rush has been formidable, ranked 6th in sacks with 45. Additionally, their ability to recover fumbles stands out as they are ranked 5th in this category.

Offensive Challenges

Quarterback play has been a concern for the Giants, with Russell Wilson and Jaxson Dart sharing duties. Wilson has thrown for 786 yards, ranking 27th, while Dart has contributed 313 yards. The team has struggled with turnovers, which has been detrimental to their offensive efficiency.

On the ground, Cam Skattebo has been a bright spot, leading the team with 240 rushing yards and 2 touchdowns. However, the rushing attack as a whole ranks 22nd, indicating room for improvement. Injuries have also impacted the running back rotation, with Tyrone Tracy Jr. and Devin Singletary contributing limited production.

Defensive Performance

The Giants’ defense has been a mix of strengths and weaknesses, ranking 24th in opponent offensive yards. They have been effective in pressuring the quarterback, which has resulted in a respectable sack total. However, their pass defense needs improvement as they rank 14th in opponent passing interceptions.

Players like Darius Muasau and Paulson Adebo have been key defensive contributors, particularly in the secondary. The Giants have shown a knack for recovering fumbles, which has helped them mitigate some of the defensive lapses. Their ability to turn over the ball will be crucial against the Eagles’ high-powered offense.

Injury Concerns

Injuries have plagued the Giants, impacting both their offensive and defensive depth. Notable players such as Graham Gano and Malik Nabers are out for extended periods. These injuries have put added pressure on backups to step up in key positions.

Jaxson Dart’s status is also worth monitoring as he deals with a hamstring issue. The Giants will need their starters to be healthy and available to compete against a tough Eagles team. The depth chart has been shuffled, and players like Wan’Dale Robinson may see increased roles.

Team Betting Trends

  • SU – Home Games (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • ATS – Home Games (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • ATS – After Loss (REG): Last 3 REG Games (2025) → 2-1 (66.7%)
  • O/U – As Underdog (REG): Last 14 REG Games (2024–2025) → 6-8 (42.9%)
  • O/U – After Loss (REG): Last 9 REG Games (2024–2025) → 4-5 (44.4%)
  • ATS – All Games (REG): Last 4 REG Games (2025) → 2-2 (50.0%)
  • ATS – As Underdog (REG): Last 4 REG Games (2025) → 2-2 (50.0%)
  • O/U – Home Games (REG): Last 4 REG Games (2024–2025) → 2-2 (50.0%)
  • O/U – All Games (REG): Last 15 REG Games (2024–2025) → 6-9 (40.0%)
  • O/U – Away Games (REG): Last 8 REG Games (2024–2025) → 3-5 (37.5%)
  • O/U – Totals ≤ 42 (REG): Last 8 REG Games (2024–2025) → 3-5 (37.5%)
  • SU – After Loss (REG): Last 5 REG Games (2024–2025) → 2-3 (40.0%)
  • SU – All Games (REG): Last 3 REG Games (2025) → 1-2 (33.3%)
  • SU – As Underdog (REG): Last 3 REG Games (2025) → 1-2 (33.3%)
  • ATS – Away Games (REG): Last 3 REG Games (2025) → 1-2 (33.3%)
  • SU – Totals ≤ 42 (REG): Last 3 REG Games (2024–2025) → 1-2 (33.3%)
  • ATS – Totals ≤ 42 (REG): Last 3 REG Games (2024–2025) → 1-2 (33.3%)
  • SU – Away Games (REG): Last 3 REG Games (2025) → 0-3 (0.0%)

Philadelphia Eagles Soar into New York: A Season Overview

Offensive Powerhouse

The Philadelphia Eagles enter Week 6 with a balanced offensive attack. They rank 2nd in rushing yards with 3048, showcasing their ground dominance. However, their passing game has been less effective, ranking 29th with 3194 yards.

Quarterback Jalen Hurts has been a key player for the Eagles, throwing for 889 yards and seven touchdowns in five games. Running back Saquon Barkley, with 267 rushing yards and three touchdowns, complements Hurts’ efforts. The Eagles have shown the ability to convert on crucial third downs, ranked 10th at 41.7%.

Defensive Stronghold

The Eagles’ defense has been formidable, allowing only 303 points, ranking 2nd in the league. Their pass rush has been effective with 41 sacks, placing them 8th overall. Additionally, they’ve been strong in turnovers, ranking 7th in interceptions with 13.

Their ability to limit opponent offensive yards is notable, ranking 1st with 4732 yards allowed. The defense also benefits from a strong presence up front, recovering 13 fumbles, which is 3rd best in the league. Players like Zack Baun and Jihaad Campbell have been pivotal in maintaining this defensive prowess.

Injury Concerns

Injuries have been a concern for the Eagles as they head into this week’s game. Key players like Saquon Barkley and Landon Dickerson are questionable, affecting both their offensive and defensive capabilities. Several players, including Ogbo Okoronkwo and Nolan Smith Jr., are on the injured reserve, impacting their depth.

With a total of 15 players listed on the injury report, managing these absences will be critical for the Eagles. The coaching staff will need to adapt their strategies to ensure competitive play against the Giants.

Upcoming Challenge: New York Giants

The Eagles face the New York Giants at MetLife Stadium as 7.5-point favorites. Philadelphia’s recent performance against the Giants suggests a competitive matchup. The Eagles’ road success is a positive indicator, with a 6-0 record in their last six away games.

Despite their status as favorites, the Eagles will need to execute effectively to secure a win. Their ability to control both the offensive and defensive lines will be key to overcoming the Giants.

Team Betting Trends

  • ATS – Away Games (REG): Last 6 REG Games (2024–2025) → 6-0 (100.0%)
  • SU – All Games (REG): Last 15 REG Games (2024–2025) → 13-2 (86.7%)
  • ATS – All Games (REG): Last 15 REG Games (2024–2025) → 13-2 (86.7%)
  • SU – As Favorite (REG): Last 14 REG Games (2024–2025) → 12-2 (85.7%)
  • ATS – As Favorite (REG): Last 14 REG Games (2024–2025) → 12-2 (85.7%)
  • SU – After Win (REG): Last 13 REG Games (2024–2025) → 11-2 (84.6%)
  • ATS – After Win (REG): Last 13 REG Games (2024–2025) → 11-2 (84.6%)
  • SU – Home Games (REG): Last 9 REG Games (2024–2025) → 8-1 (88.9%)
  • SU – Away Games (REG): Last 6 REG Games (2024–2025) → 5-1 (83.3%)
  • ATS – Home Games (REG): Last 9 REG Games (2024–2025) → 7-2 (77.8%)
  • O/U – All Games (REG): Last 3 REG Games (2025) → 2-1 (66.7%)
  • O/U – As Favorite (REG): Last 3 REG Games (2025) → 2-1 (66.7%)
  • O/U – Away Games (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • O/U – After Win (REG): Last 3 REG Games (2025) → 2-1 (66.7%)
  • O/U – Home Games (REG): Last 5 REG Games (2024–2025) → 2-3 (40.0%)

Giants vs Eagles Prediction: Eagles -7.5

The Philadelphia Eagles come into this game with a strong 4-1 record and are undefeated on the road. Their offense ranks high in rushing yards, which could exploit the Giants’ 22nd-ranked rushing defense from last season. With a solid defensive unit that ranked second in points allowed last season, the Eagles have the potential to dominate the Giants on both sides of the ball.

Meanwhile, the New York Giants have struggled with a 1-4 record this season and have not performed well within their division. Their offensive struggles, as seen by their 29th rank in scoring last season, are concerning against a formidable Eagles defense. Moreover, the Giants’ recent head-to-head performances against the Eagles have not been favorable, as evidenced by their losses in the previous two encounters.

Given the Eagles’ impressive road record and defensive superiority, taking them to cover the -7.5 spread appears to be the wise choice. The Eagles have managed to cover the spread in recent matchups against the Giants, and their current form suggests they can do so again.

In conclusion, the Eagles should overpower the Giants with their high-ranked rushing attack and stout defense, leading to a comfortable win. The predicted final score favors the Eagles at MetLife Stadium.

  • Giants vs Eagles Prediction: Eagles -7.5
  • Giants vs Eagles Score: Eagles 28 – Giants 14
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