San Francisco 49ers vs Tampa Bay Buccaneers Matchup

Read our 49ers vs Buccaneers pick and preview for this NFL pre-season week 10 game in Tampa Bay. Check out who we like to win and cover the spread in this regular season NFL matchup.

The 49ers are favored on the road with a money line of -245 as they take on the Buccaneers at 1:00 ET on Sunday, November 10th. The over/under line is set at 51 points, and San Francisco is -5.5 point favorites on the road. The Buccaneers' money line odds are +204. This week 10 matchup is being televised on FOX.

49ers vs. Buccaneers Matchup At A Glance

Sport: NFL
Teams: San Francisco 49ers at Tampa Bay Buccaneers
Where: Tampa Bay at Raymond James Stadium
Date: Sunday, November 10th
Betting Odds SF -5.5, SF -245 | TB +204 O/U 51

49ers Preview:

Heading into week 10, the 49ers sit at 4-4 after a 30-24 win over the Cowboys in week 8. San Francisco was favored by 5.5 points and covered the spread with the victory. The O/U line was 47.5, and the teams combined for 54 points. Before this, the 49ers had lost two straight, including a 28-18 loss to the Chiefs in week 7.

Despite their .500 record, the 49ers rank 6th in our NFL power rankings and have a 40.4% chance of making the playoffs. They’ve been favored in all of their games so far and are 4-4 against the spread. Their O/U record is 5-3, with their games averaging 49 points per contest.

49ers Offense Breakdown

San Francisco heads into week 10 ranked 10th in our offensive power rankings. They are 6th in the NFL in points per game (26.2) and 2nd in yards per game (412.4). Despite ranking 19th in passing attempts, they are 4th in passing yards, averaging 253.4 per game. On the ground, they rank 7th in rushing attempts and 4th in rushing yards, with 159 per game. They have struggled in the red zone, converting just 17.1% of their attempts, which ranks 22nd in the league.

Brock Purdy bounced back from a rough outing in week 7, where he threw 3 interceptions, with a strong performance in week 8 against the Cowboys. He completed 18 of 26 passes for 260 yards and a touchdown, posting a passer rating of 114. George Kittle led the team with 6 catches for 128 yards, and Isaac Guerendo added 85 rushing yards on 14 carries. Deebo Samuel, who had 102 receiving yards in week 6, is questionable for week 10 with a rib injury.

49ers Team Defense

In their 30-24 win over the Cowboys, the 49ers' defense allowed just 56 rushing yards on 19 attempts, giving up only 2.9 yards per attempt on the ground. They defended 236 passing yards, with two interceptions and two sacks. The 49ers also held Dallas to a 33.3% conversion rate on third down.

Despite allowing two passing touchdowns, the 49ers' defense made key plays to help secure the win, including forcing two turnovers. They also pressured the quarterback effectively, finishing with a +6 advantage in quarterback hits and a +2 advantage in tackles for loss.

Buccaneers Preview:

The Buccaneers enter week 10 against the 49ers looking to snap a three-game losing streak. After a 51-27 win over the Saints in week 6, Tampa Bay has dropped three straight, including a 30-24 loss to the Chiefs in week 9. Despite the loss, they covered the 8.5-point spread, bringing their ATS record to 5-4. Their O/U record is 7-2, with the over hitting in six straight games.

With a 4-5 record, the Bucs have a 40.8% chance of making the playoffs and a 19.7% chance of winning the NFC South. They rank 11th in our NFL power rankings and 2nd in the division. Tampa Bay is 2-3 at home and 2-2 on the road.

Buccaneers Offense Breakdown

Heading into week 10, the Buccaneers rank 7th in our offensive power rankings, averaging 28.8 points per game, which is 5th in the NFL. They also rank 5th in passing yards per game (250.8) and 10th in rushing yards, despite being 22nd in rushing attempts. Tampa Bay has been strong on 3rd down, converting 51.8% of their attempts, which ranks 2nd in the league.

Baker Mayfield threw for 200 yards and 2 touchdowns in week 9, posting a passer rating of 112. Cade Otton led the team in receiving with 8 catches for 77 yards and a touchdown, while Bucky Irving had 24 rushing yards on 7 carries. Tampa Bay scored 10 points in the 3rd quarter against Kansas City after trailing at halftime.

Buccaneers Team Defense

In their 30-24 overtime loss to the Chiefs, the Buccaneers allowed three passing touchdowns and gave up 260 yards through the air. The defense struggled to get off the field, as Kansas City converted 66.7% of their third down attempts. Despite this, they did manage to sack Patrick Mahomes four times and hit him three more times than the Chiefs hit Tom Brady.

The Chiefs completed 77.3% of their passes against Tampa Bay and finished with 384 total yards. The Buccaneers also defended the run decently, giving up 124 yards on 35 attempts (3.5 yards per attempt).

49ers vs Buccaneers Betting Odds, Trends & Analysis

Through their last five road contests, the 49ers offense has averaged 25 points per game while allowing an average of 21. San Francisco posted an overall record of 2-3 while going 2-3 ATS.
Across their ten previous home games, Tampa Bay has an ATS mark of 7-3. Their straight up record in these matchups was 5-5 while averaging 25 points per game.
The last ten games that Tampa Bay was the underdog, they have an ATS mark of 6-4 while going 5-5 straight up.
Spanning across their last ten games as the betting favorite, the 49ers have gone 4-6 vs the spread. Their overall record in these games was 5-5.