Read on to get betting odds and analysis in our week 3 Chargers vs Steelers pick and preview and see who we think will win and cover in Pittsburgh.
The Chargers and Steelers will face off on Sunday, September 22nd at 1:00 ET on CBS. The game, being played at Acrisure Stadium in Pittsburgh, is a week three AFC matchup. The Chargers are the road team and the money line underdog at +105, while the Steelers are favored at -126. The point spread is -2 in favor of the Steelers, with the over/under line set at 35.5 points.
Chargers vs. Steelers Matchup At A Glance
- Sport: NFL
- Teams: Los Angeles Chargers at Pittsburgh Steelers
- Where: Pittsburgh at Acrisure Stadium
- Date: Sunday, September 22nd
- Betting Odds PIT -2, LAC +105 | PIT -126 O/U 35.5

Chargers Preview:
After a 26-3 win over the Panthers, the Chargers are now 2-0 in the regular season. Los Angeles took a 6-0 lead in the 1st quarter and then added two more touchdowns in the 2nd quarter to go up 20-0 at halftime. The Chargers capped off their win with a touchdown to Ladd McConkey in the 4th quarter.
Heading into the game, the Chargers were -4.5 point favorites, and with the 23-point win, they covered the spread. The combined 29 points fell short of the over/under line of 38.5 points.
Chargers Offense Breakdown
The Chargers' offense put up 26 points in their 26-3 win over the Panthers, and they were able to run the ball effectively, gaining 219 yards on 44 attempts. Despite struggling in the passing game with just 130 yards, Justin Herbert threw two touchdowns and completed 70% of his passes. Herbert's longest pass went for 29 yards to Quentin Johnston, who finished with two touchdown catches.
J.K. Dobbins was the leading rusher with 131 yards, averaging 7.7 yards per attempt and scoring one touchdown, with a long run of 43 yards. Los Angeles finished the game with 21 first downs and a 56.2% conversion rate on third down.
Chargers Team Defense
In their 26-3 win over the Panthers, the Chargers' defense was dominant, allowing just 69 passing yards and forcing Carolina to complete only 18 passes. The Panthers managed just 159 total yards and were held to 3% on third down conversions. The Chargers' run defense allowed 90 yards on 18 attempts, giving up 5 yards per attempt, but overall, their pass defense was excellent.
Los Angeles also came away with one interception and two sacks, and they limited the Panthers to just 8.3% on third down conversions. The Chargers' defense didn't allow a single touchdown in the game.Steelers Preview:
After a 26-3 win over the Panthers, the Chargers are now 2-0 in the regular season. Los Angeles took a 6-0 lead in the 1st quarter and then added two more touchdowns in the 2nd quarter to go up 20-0 at halftime. The Chargers capped off their win with a touchdown to Ladd McConkey in the 4th quarter.
Heading into the game, the Chargers were -4.5 point favorites, and with the 23-point win, they covered the spread. The combined 29 points fell short of the over/under line of 38.5 points.
Steelers Offense Breakdown
The Steelers' offense struggled to move the ball through the air in their 13-6 win over the Broncos, finishing with just 110 yards passing. Pittsburgh's running game was more effective, gaining 141 yards on 36 attempts. Justin Fields, who went 13/20 for 117 yards and one touchdown, was the leading passer, while Najee Harris rushed for 69 yards to lead the team.
Pittsburgh finished with 16 first downs and 295 total yards. Harris had 17 carries and a long run of 11 yards. Pat Freiermuth was the top receiver with 39 yards on four catches. The Steelers were not very efficient on third down, converting only 30.8% of their chances.
Steelers Team Defense
In their 13-6 win over the Broncos, the Steelers' defense was dominant on third downs, allowing just a 16.7% conversion rate. They also forced two interceptions and held Denver to 64 rushing yards on 19 attempts. Pittsburgh gave up 231 passing yards on 20 completions, but didn't allow any passing touchdowns.
The Steelers' defense pressured the quarterback consistently, coming away with two sacks and holding Denver to a 57.1% completion percentage. Pittsburgh's defense didn't allow a single point in the second half of the game.Chargers vs Steelers Betting Odds, Trends & Analysis
- Through their last five road games, Los Angeles has an ATS record of just 2-3. However, their overall record was 2-3 while averaging 16 points per game.
- The Steelers are 2-1 ATS in their last three home games and 2-1 straight-up.
- In their last five games as the betting underdog, the Chargers have a straight up record of 0-5 and an ATS mark of 1-4.
- Pittsburgh has done well both straight up and vs the spread when favored to win the game, going 2-1 SU and 2-1 ATS in their last three games.
Chargers vs Steelers Free Pick
- KnupSports.com Free Betting Pick: Chargers +2 Be sure to check out our other NFL Football betting previews for this week. KnupSports.com also updates their sports betting picks page daily with plays across all sports.