Kansas City Chiefs vs San Francisco 49ers Matchup

In this week 7 NFL regular season preview between Chiefs and 49ers, see who like to win the game and cover the spread.

The 49ers are favored at -121 on the money line as they host the Chiefs at 4:25 ET on Sunday, October 20th at Levi's Stadium in Santa Clara, CA. The Chiefs are +101 on the money line, and the point spread is tight, with the 49ers at -1.5. This week seven non-conference matchup is being televised on FOX, and the over/under line is set at 46.5 points.

Chiefs vs. 49ers Matchup At A Glance

Sport: NFL
Teams: Kansas City Chiefs at San Francisco 49ers
Where: Santa Clara at Levi's Stadium
Date: Sunday, October 20th
Betting Odds SF -1.5, KC +101 | SF -121 O/U 46.5

Chiefs Preview:

Heading into week 7, the Chiefs sit atop the AFC with a 5-0 record, giving them a 99.2% chance of making the playoffs and a 93.7% chance of winning the AFC West. They are 3rd in our NFL power rankings. Kansas City is 3-1-1 against the spread this season, having been favored in all of their games. Their average scoring margin is +6.6 points per game.

In week 5, the Chiefs covered the spread in a 26-13 win over the Saints, improving to 5-0. The O/U line was 43 points, and the teams combined for 39. The under has hit in three straight Chiefs games. Their O/U record is 2-3 this season.

Chiefs Offense Breakdown

Heading into week 7, the Chiefs are 13th in the NFL in scoring, averaging 23.6 points per game. They rank 11th in total offense with 354.6 yards per game, including 236.8 passing yards per game, which is 9th in the league. Kansas City is 16th in rushing, with 117.8 yards per game on the ground, on 30 attempts per game. They rank 8th in 3rd-down conversions and have a 50% red zone conversion rate, also 8th in the NFL.

Patrick Mahomes threw for 331 yards in week 5, completing 28 of 39 passes, but did not have a touchdown pass and threw one interception. JuJu Smith-Schuster led the team with 130 receiving yards on 7 catches, while Kareem Hunt rushed for 102 yards and a touchdown on 27 carries. Kansas City scored 10 points in the 4th quarter against the Saints in week 5.

Chiefs Team Defense

In their 26-13 win over the Saints, the Chiefs' defense allowed just 46 rushing yards on 15 attempts. The Chiefs gave up 174 passing yards on 20 completions, with the Saints finishing with 220 total yards. Despite their good performance, they did allow two passing touchdowns. They also forced one interception and held the Saints to a 57.1% completion rate.

On third downs, the Chiefs held the Saints to a 40% conversion rate. They managed one sack and held the Saints to 5 yards per pass attempt.

49ers Preview:

Heading into week 7, the 49ers are 3-3, putting them 1st in the NFC West despite a 1-2 division record. Our power rankings have them 4th in the NFL, and they have a 57.5% chance of winning the division and a 62.7% chance of making the playoffs. San Francisco has been favored in all of their games so far and is 3-3 against the spread, with an average scoring margin of +5.3 points per game. Their O/U record is 4-2, with their games averaging 48.7 points compared to an average line of 45.8.

After losing to the Cardinals in week 5, the 49ers bounced back with a 36-24 win over the Seahawks in week 6. They were 3.5-point favorites in that game and covered the spread, improving their record to 3-3. The O/U line was 49 points, and the teams combined for 60. In week 4, the 49ers beat the Patriots 30-13, but they couldn’t carry that momentum into week 5, losing 24-23 to Arizona as 7-point favorites.

49ers Offense Breakdown

Our offensive power rankings have the 49ers at 6th in the NFL, and they are 7th in points per game, averaging 27. San Francisco has been strong on the ground, ranking 4th in rushing attempts and 3rd in rushing yards per game, with 158. They also rank 2nd in passing yards per game, despite being 18th in passing attempts. On 3rd down, they convert 45.7% of the time, which ranks 5th in the league, and they lead the NFL in red zone attempts, although their conversion rate of 14.8% ranks 23rd.

Brock Purdy had a strong performance in week 6, throwing for 255 yards and 3 touchdowns without an interception, finishing with a passer rating of 129. Deebo Samuel Sr. led the team with 102 receiving yards on 3 catches, while Isaac Guerendo had 99 rushing yards on 10 carries. The 49ers scored 13 points in both the 2nd and 4th quarters against Seattle.

49ers Team Defense

In their 36-24 win over the Seahawks, the 49ers' defense allowed 306 passing yards on 30 completions. Despite this, they held Seattle to just 52 rushing yards on 20 attempts. The defense also came up with two interceptions and limited the Seahawks to a 43.8% conversion rate on third down.

San Francisco gave up 358 total yards in the game and allowed one passing touchdown. They finished with one sack and came out ahead in the quarterback hit battle. The 49ers' defense forced Seattle to rely heavily on the passing game and held them to just 2.6 yards per attempt on the ground.

Chiefs vs 49ers Betting Odds, Trends & Analysis

In their last three road games, Kansas City has averaged 18 points per game while allowing 12. The team's record in this stretch was 3-0 while going 2-0-1 vs. the spread.
Through their last ten home games, San Francisco has an ATS record of just 6-4. However, their overall record was 6-4 while averaging 29 points per game.
In their last five games as the betting underdog, the Chiefs have a strong straight up record of 5-0. In addition, their ATS record was 5-0 in these scenarios.
In their last three games as the betting favorite, the 49ers have a strong straight up record of 2-1. In addition, their ATS record was 2-1 in these scenarios.