Keep reading to see our NFL week 17 Colts vs Giants pick and preview. In this article we will outline who will come away with the win and cover the spread.
The money line odds have the Colts as -418 road favorites as they take on the Giants at 1:00 ET on Sunday, December 29th at MetLife Stadium in East Rutherford, NJ. The Giants are +322 on the money line, and FOX is televising this week 17 non-conference matchup. The Colts are favored by -7.5 points, with the over/under line set at 40.5 points.
Colts vs. Giants Matchup At A Glance
- Sport: NFL
- Teams: Indianapolis Colts at New York Giants
- Where: East Rutherford at MetLife Stadium
- Date: Sunday, December 29th
- Betting Odds IND -7.5, IND -418 | NYG +322 O/U 40.5

Colts Preview:
Heading into week 17 with a 7-8 record, the Colts have a 13% chance of making the playoffs, but they are out of the running for the AFC South title. After losing to the Broncos in week 15, Indianapolis bounced back with a 38-30 win over the Titans in week 16. They were 4-point favorites in that game and covered the spread, improving their ATS record to 9-6.
So far, the over has hit in three straight Colts games, including week 16, when they and the Titans combined for 68 points. The O/U line for that matchup was 42.5. On average, Colts games have featured 45.1 points this season, compared to an average line of 44.3.
Colts Offense Breakdown
Heading into week 17, the Colts rank 27th in our offensive power rankings. They are 21st in the NFL in points per game (21.2) and 21st in yards per game (321.1). They rank 28th in passing yards per game, with 185.9, on 29 attempts per game. On the ground, they are 8th in rushing attempts (28.6 per game) and rushing yards, averaging 135.2 per game. Indianapolis ranks 21st in 3rd-down conversions, with a 37.2% success rate, and they are 12th in red zone conversion percentage.
Jonathan Taylor is coming off a huge performance in week 16, rushing for 218 yards and 3 touchdowns on 29 carries. Anthony Richardson threw for 131 yards, completing 7 of 11 passes, with 1 touchdown and 1 interception. Josh Downs led the team with 61 receiving yards on 3 catches. The Colts scored 38 points against the Titans, with 24 coming in the 2nd quarter and 14 in the 3rd.
Colts Team Defense
In their 38-30 win over the Titans, the Colts' defense gave up 242 yards through the air, with Tennessee completing 67.6% of their passes. They also allowed 2 passing touchdowns and struggled on third downs, allowing the Titans to convert 45.5% of their third down attempts. Despite this, the Colts' defense came up with 3 interceptions to help secure the win.
Indianapolis defended the run well, allowing just 65 yards on 22 attempts. They also managed one sack and had more QB hits and tackles for loss than the Titans.Giants Preview:
Heading into week 17, the Giants are on a 10-game losing streak, dropping their record to 2-13. New York sits 31st in our NFL power rankings and has been eliminated from playoff contention. They are 0-8 at home this season and 2-5 on the road, with both wins coming in weeks 3 and 5 against the Browns and Seahawks, respectively.
Against the spread, the Giants are 4-11, with an average scoring margin of -9.8 points per game. They are 4-10 as underdogs and 0-1 as favorites. Their O/U record is 5-10, with their games averaging 38.5 points per game compared to an average line of 41.7.
Giants Offense Breakdown
Heading into week 17, the Giants rank 30th in our offensive power rankings. They are 31st in the NFL in scoring, averaging 14.3 points per game, and they sit last in the league in total offense, with 292.3 yards per game. Despite being 7th in passing attempts, they rank 29th in passing yards per game (185.4). On the ground, they are 20th in rushing attempts and 22nd in rushing yards per game, averaging 106.9 yards.
In week 16, the Giants scored just 7 points, all in the 2nd quarter, in their loss to the Falcons. Drew Lock threw for 210 yards, going 22 of 39, with 1 touchdown and 2 interceptions. Malik Nabers led the team with 7 catches for 68 yards, while Tyrone Tracy Jr. had 26 rushing yards on 7 carries. New York converted 33.3% of their 3rd-down attempts and scored on 1 of 2 red zone trips.
Giants Team Defense
The Giants' defense struggled to generate pressure in their most recent game, failing to record any sacks and losing the quarterback hit differential by -4. Despite allowing just 18 completions, the Giants gave up 202 passing yards to the Falcons. In the running game, they allowed 127 yards on 38 attempts. Overall, the Giants lost 34-7, and their defense allowed the Falcons to convert on 57.1% of their third down attempts.
New York's defense did come up with one interception and limited the Falcons to a 66.7% completion percentage. However, they were unable to keep Atlanta out of the end zone, as the Falcons scored four touchdowns.Colts vs Giants Betting Odds, Trends & Analysis
- In their last five games away from home, the Colts have a straight up record of 2-3 while going 2-3 vs the spread. The team's offense averaged 19 points per game in these contests.
- When looking at their past three home matchups, New York has an ATS record of 0-3 while averaging 14 per game. The team went 0-3 overall in these games.
- Going back to their previous ten games as the underdog, New York has an ATS mark of 2-8 while going 1-9 straight up.
- Through their last three games as the favorite, the Colts have an ATS record of 2-1 and a straight up mark of 3-0.
Colts vs Giants Free Pick
- KnupSports.com Free Betting Pick: Colts -7.5 Be sure to check out our other NFL Football betting previews for this week. KnupSports.com also updates their sports betting picks page daily with plays across all sports.