Buffalo Bills vs Jacksonville Jaguars Matchup

Read on to get betting odds and analysis in our week 3 Jaguars vs Bills pick and preview and see who we think will win and cover in Orchard Park.

The Jaguars and Bills will face off on Monday, September 23rd at 7:30 ET, with ESPN covering the week three AFC matchup. The game, being played at Highmark Stadium in Orchard Park, NY, has the Bills favored at -257 on the money line and -5.5 on the point spread. The over/under line is set at 45.5 points.

Jaguars vs. Bills Matchup At A Glance

Sport: NFL
Teams: Jacksonville Jaguars at Buffalo Bills
Where: Orchard Park at Highmark Stadium
Date: Monday, September 23rd
Betting Odds BUF -5.5, JAX +210 | BUF -257 O/U 45.5

Jaguars Preview:

The Jaguars are now 0-2 after their 18-13 loss to the Browns. Jacksonville fell behind early, with Deshaun Watson scoring on a 1-yard touchdown run in the 1st quarter. Favored by -3 at home, the Jaguars were unable to cover the spread. The over/under line for the game was 41.5 points, and the teams combined for 31.

Jacksonville battled back after trailing 13-3 at halftime, with Trevor Lawrence's 22-yard touchdown run and a 22-yard field goal from Cam Little closing the gap to 13-6 in the 2nd quarter. Lawrence connected with Brian Thomas Jr. for a touchdown in the 3rd quarter, and another field goal from Little made it a 16-13 game in the 4th. However, the Browns added a late touchdown to seal the win.

Jaguars Offense Breakdown

The Jaguars' offense struggled in their 18-13 loss to the Browns, managing just 13 points. They finished with 18 first downs and 127 yards on 21 rushing attempts. However, they were unable to find the endzone through the air, as quarterback Trevor Lawrence completed just 14 of 30 passes for 196 yards. He was also sacked four times.

Travis Etienne Jr. led the team with 52 rushing yards and scored the team's only touchdown. Brian Thomas Jr. was the top receiver with 94 yards, 66 of which came on one catch. Lawrence finished with a passer rating of 71 and was unable to guide the Jaguars to a comeback victory.

Jaguars Team Defense

In their 18-13 loss to the Browns, the Jaguars' defense held Cleveland to just 5.1 yards per attempt in the passing game, giving up 172 yards through the air. However, they struggled to stop the run, allowing 125 yards on 29 attempts (4.3 yards per attempt). Jacksonville also limited the Browns to a 14.3% third-down conversion rate and recorded two sacks.

Despite their efforts, the Jaguars couldn't come out with a win. Their run defense was a key issue, and they will look to improve in this area in the next game.

Bills Preview:

Bills Offense Breakdown

Josh Allen completed 13 of 19 passes for 139 yards and one touchdown in Buffalo's 31-10 win over the Dolphins. The Bills' offense finished with 13 first downs and 108 yards on the ground. Allen was not sacked in the game and had a passer rating of 107.

James Cook led the rushing attack with 78 yards on 11 carries, including two touchdowns and a 49-yard run. Khalil Shakir was the top receiver with 54 yards on five catches. The Bills struggled on third down, converting only 33.3% of their chances.

Bills Team Defense

In their 31-10 win over the Dolphins, the Bills' defense picked off three passes and held Miami to just 5.4 yards per attempt in the passing game. Despite giving up 139 rushing yards on 34 attempts, Buffalo's defense allowed just one touchdown and limited the Dolphins to a 64.1% completion percentage. They also forced Miami to convert on only 46.7% of their third down attempts.

Buffalo's defense recorded two sacks in the game and had more tackles for loss and quarterback hits than the Dolphins. The Bills' secondary played well, despite allowing 212 passing yards.

Jaguars vs Bills Betting Odds, Trends & Analysis

In their last ten games away from home, the Jaguars have a straight up record of 5-5 while going 7-3 vs. the spread. The team averaged 22 points per game in this stretch.
In their last five home games, Buffalo has averaged 26 points per game while allowing 20. The team's record in this stretch was 4-1 while going 3-2 vs. the spread.
Spanning across their last five games as the betting underdog, the Jaguars have gone 2-3 vs the spread. Their overall record in these games was 1-4.
Against the spread, the Bills have put together 1-2 in their last three games as the betting favorite. In these same games, they went 2-1 straight up.