NFL Game Prediction

Falcons vs Bills Prediction & Betting Tips for NFL Week 6 on 10/13/2025

Want our best Falcons vs Bills prediction for NFL week 6 on 10/13/25? Get our NFL betting tip as the Buffalo Bills travel to the Atlanta Falcons on 10/13/25 at Mercedes-Benz Stadium, in Atlanta. Knup Sports has your free pick!

The Buffalo Bills are set to play against the Atlanta Falcons in a Week 6 contest of the 2025 NFL season. The game will take place at the Mercedes-Benz Stadium in Atlanta, featuring a retractable roof which may mitigate any adverse weather conditions. Fans can catch the action on ESPN with kickoff scheduled for 7:15 PM. The Bills, led by head coach Sean McDermott, currently hold a 4-1-0 record for the season. They have shown strong performance both at home and on the road, with a road record of 1-0-0. In their recent games, the Bills suffered a narrow 23-20 loss to the New England Patriots but previously secured wins against the New Orleans Saints and Miami Dolphins. The Falcons, under head coach Raheem Morris, enter the game with a 2-2-0 record. They recently achieved a 34-27 victory against the Washington Commanders but faced a challenging 30-0 defeat to the Carolina Panthers. Playing at home, the Falcons aim to improve their 1-1-0 home record against the formidable Bills.

Falcons vs Bills At a Glance

  • Game Location: Mercedes-Benz Stadium in Atlanta, GA
  • Current Records: Buffalo Bills 4-1, Atlanta Falcons 2-2
  • Game Time: Monday, October 13, 2025, at 7:15 PM
  • TV Coverage: ESPN
  • Weather Conditions: Retractable Roof; wind conditions and temperature not specified
  • Game Odds: Bills Moneyline -216, Falcons Moneyline +180

Analyzing the Atlanta Falcons: A Deep Dive into Their 2025 Season

Falcons Offensive Overview

The Atlanta Falcons have shown a strong offensive presence with a total score of 389, ranking them 13th in the league. Their passing game is particularly noteworthy, as they amassed 4,068 passing yards, securing the 5th spot in the rankings. Additionally, their ground game contributed 2,219 rushing yards, placing them in the 10th position.

First downs have been a significant aspect of their offensive strategy, with 359 total first downs, ranking 7th overall. Their third down conversion rate stands at 39.2%, positioning them at 15th in the league, indicating room for improvement in maintaining drives.

Falcons Defensive Insights

Defensively, the Falcons have allowed 423 points, placing them 22nd in the league. They recorded 31 sacks, which ties them for 17th in this category. The defense has been relatively successful in forcing turnovers, intercepting 12 passes, ranking 8th.

Furthermore, the Falcons recovered six fumbles, earning them a 9th-place ranking. However, they allowed a total of 5,868 opponent yards, positioning them at 23rd, indicating a need for tightening their defensive play.

Recent Game Performances

In their recent victory against the Washington Commanders, the Falcons displayed offensive prowess with 307 passing yards and 128 rushing yards. Bijan Robinson and Michael Penix Jr. were standout performers, with Robinson rushing for 75 yards and scoring a touchdown.

The Falcons faced a challenging game against the Carolina Panthers, resulting in a 30-0 loss. Despite gaining more first downs and passing yards than the Panthers, turnovers were a critical issue, with two interceptions thrown by Michael Penix Jr.

Injury Concerns

The Falcons are dealing with significant injury concerns, with key players such as Storm Norton and Kaleb McGary on the injured reserve list. Several players, including KhaDarel Hodge and Darnell Mooney, are questionable for upcoming games due to various injuries.

These injuries could impact the Falcons’ depth and overall performance, especially if key contributors like A.J. Terrell Jr. and Nathan Carter are unable to play at full capacity in upcoming games.

Team Betting Trends

  • ATS – As Favorite (REG): Last 8 REG Games (2024–2025) → 7-1 (87.5%)
  • ATS – After Loss (REG): Last 5 REG Games (2024–2025) → 4-1 (80.0%)
  • ATS – Home Games (REG): Last 4 REG Games (2024–2025) → 3-1 (75.0%)
  • ATS – All Games (REG): Last 8 REG Games (2024–2025) → 5-3 (62.5%)
  • SU – As Favorite (REG): Last 8 REG Games (2024–2025) → 5-3 (62.5%)

The Buffalo Bills Charge Into Atlanta: Analyzing Their Performance and Trends

Buffalo Bills Offensive Strength

The Buffalo Bills have demonstrated a powerful offense in the 2024 season, ranking 2nd in total score with 525 points. Their passing game has been strong, ranking 9th with 3,875 yards, while their rushing attack has matched this ranking with 2,230 yards.

They have also been efficient in moving the chains, securing 360 first downs, which ranks them 6th in the league. The Bills’ offense has been adept at converting on third downs, boasting a 44.1% conversion rate, good for 7th overall.

Defensive Prowess and Challenges

The Bills’ defense has shown solid performance, allowing only 368 points, placing them 11th in the league. They have been effective at pressuring quarterbacks with 39 sacks, ranking 10th.

The defense has excelled in creating turnovers, with 16 interceptions and 16 fumble recoveries, ranking 4th and 1st, respectively. However, they have allowed 5,806 opponent offensive yards, ranking 17th, indicating room for improvement in yardage control.

Recent Game Recaps

In their recent game against the New England Patriots, the Bills fell short in a close 23-20 loss despite having more first downs and rushing yards than their opponents. Key offensive players like Josh Allen and Dalton Kincaid made significant contributions, though Allen’s interception may have proved costly.

Previously, the Bills secured a 31-19 victory over the New Orleans Saints, with a balanced attack featuring both passing and rushing success. Josh Allen led the way with two touchdowns, complemented by James Cook’s strong rushing performance.

Player Highlights

Quarterback Josh Allen has been a standout performer for the Bills, leading the league with 1,217 passing yards and 9 touchdowns through five games. His 117.9 fantasy points are a testament to his consistent production.

Running back James Cook has also been a key contributor, ranking 2nd in rushing yards with 450 and adding 5 touchdowns. Dalton Kincaid has emerged as a reliable target, leading the team in receiving yards among tight ends with 287 and scoring 3 touchdowns.

Team Betting Trends

  • SU – Home Games (REG): 8-1 (88.9%) in last 9 REG games.
  • O/U – Totals ≥ 50 (REG): 4-0 (100.0%) in last 4 REG games.
  • SU – All Games (REG): 12-3 (80.0%) in last 15 REG games.
  • ATS – Away Games (REG): 5-1 (83.3%) in last 6 REG games.
  • O/U – Away Games (REG): 4-1 (80.0%) in last 5 REG games.

Falcons vs Bills Prediction: Over 49.5

The Buffalo Bills have been a formidable offensive team, ranking second in scoring with 525 points last regular season. Their powerful offense, led by Offensive Coordinator Joe Brady, suggests they have the potential to score high against the Falcons. Additionally, the Bills have a road record of 1-0 this season, proving they can perform well away from home.

On the other hand, the Atlanta Falcons, despite their 2-2 record, have shown they can move the ball effectively. Ranking fifth in passing yards last season, they have the capability to challenge the Bills’ defense. Under the direction of Offensive Coordinator Zac Robinson, they are poised to put up points, especially in a controlled environment like the Mercedes-Benz Stadium.

Given the offensive strengths of both teams and their previous scoring trends, the 49.5 total seems attainable. The Falcons’ last few home games have shown a tendency to go over the total, which further supports a high-scoring game. With both teams’ offensive capabilities, it’s likely that the total will surpass the current line.

Considering the offensive firepower on both sides, a projected final score could be Buffalo Bills 31 – Atlanta Falcons 24, resulting in a combined score that exceeds the total of 49.5. This aligns with both teams’ recent performances and the overall dynamics of the matchup.

  • Falcons vs Bills Prediction: Over 49.5
  • Falcons vs Bills Score: Bills 31 – Falcons 24
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