CFB Game Prediction

Eastern Michigan vs Louisiana-Lafayette Prediction & Betting Tips for CFB Week 4 on 9/20/2025

Want our best Eastern Michigan vs Louisiana-Lafayette prediction for 9/20/25? Get our College Football betting tip as the Louisiana-Lafayette travel to Eastern Michigan in Week 4 on 9/20/25 at Rynearson Stadium, in Eastern Michigan. Knup Sports has your free CFB pick!

In Week 4 of the 2025 College Football season, the Louisiana-Lafayette Ragin’ Cajuns head to Ypsilanti, Michigan to play against the Eastern Michigan Eagles. This game is set for Saturday, September 20, 2025, with a kickoff at 3:30 PM at Rynearson Stadium. Fans can catch the action live on ESPN+.

Louisiana-Lafayette enters the game with a 1-2 record, looking to bounce back after a tough loss against Missouri, 52-10. Despite their recent challenges on the road, they will aim to capitalize on their strong rushing attack, which was on display in their 34-10 victory against McNeese State earlier this season.

Eastern Michigan, still searching for their first win of the season, holds a 0-3 record. The Eagles have struggled defensively, allowing over 40 points in two of their first three games. Playing at home, they will look to utilize their passing game, which saw them rack up 330 yards against Kentucky, to challenge the Ragin’ Cajuns’ defense.

Eastern Michigan vs Louisiana-Lafayette At a Glance

  • Game Location: Rynearson Stadium in Ypsilanti, MI
  • Game Time: Saturday, September 20, 2025 at 3:30 PM
  • Broadcast: ESPN+
  • Current Records: Louisiana-Lafayette 1-2, Eastern Michigan 0-3
  • Betting Lines: Louisiana-Lafayette favored with a -2.5 spread
  • Weather: Outdoor field, check local forecasts for updates

Eastern Michigan Eagles: Seeking Redemption on the Road

Offensive Performance

The Eastern Michigan Eagles have demonstrated a moderate offensive output so far this season, amassing 767 passing yards which positions them at 45th in the nation. Their rushing game has struggled to gain traction, accumulating 396 yards and ranking 84th.

Despite these challenges, the Eagles have been effective in moving the chains, securing 61 first downs, earning them the 26th spot in this category.

Defensive Struggles

Defensively, Eastern Michigan has faced significant challenges, conceding 128 points, placing them at 94th in points against. Their pass rush has shown potential with a single sack, but they have yet to record an interception.

Moreover, the Eagles are still seeking their first fumble recovery, which remains a crucial aspect to improve as they aim to tighten their defensive stand.

Key Players to Watch

Quarterback Noah Kim has been a standout for the Eagles, with a commendable 767 passing yards and four touchdowns, highlighting his importance to their aerial attack. Running back Dontae McMillan has been the most productive on the ground, rushing for 219 yards and adding a touchdown to his tally.

Wide receiver Terry Lockett Jr. has been a reliable target, with 230 receiving yards and a touchdown, providing a spark in the passing game.

Recent Game Recaps

The Eagles have faced a tough start to their season, with their most recent game resulting in a 48-23 loss to the Kentucky Wildcats. In that encounter, Eastern Michigan managed to accumulate 330 passing yards but struggled to contain Kentucky’s potent rushing attack.

Earlier, they suffered a narrow 28-23 defeat at the hands of the LIU Sharks, a game where their defensive frailties were once again exposed.

Upcoming Challenges

Eastern Michigan will host the Louisiana-Lafayette Ragin’ Cajuns next, a game where they will be looking to leverage their home advantage at Rynearson Stadium. They will then travel to face the Central Michigan Chippewas, followed by an away game against the Buffalo Bulls.

These upcoming fixtures present opportunities for the Eagles to turn their season around, but they will need significant improvements on both sides of the ball.

Team Betting Trends

  • SU – As Favorite: 16-6 (72.7%) in last 22 games (2020–2025)
  • O/U – Home Games: 6-2 (75.0%) in last 8 games (2023–2025)
  • ATS – As Underdog: 13-7 (65.0%) in last 20 games (2022–2025)
  • ATS – After Win: 9-4 (69.2%) in last 13 games (2022–2024)
  • ATS – Away Games: 12-7 (63.2%) in last 19 games (2022–2025)
  • SU – After Loss: 15-10 (60.0%) in last 25 games (2020–2025)

The Road Challenge Ahead for Louisiana-Lafayette Ragin’ Cajuns

Season Overview

The Louisiana-Lafayette Ragin’ Cajuns enter their upcoming game with a mixed start to their 2025 season. They currently hold a 1-2 record, highlighted by a decisive win over McNeese State Cowboys but challenging losses to Rice Owls and Missouri Tigers. Their performance against the Tigers, where they fell 52-10, exposed some areas that need improvement.

In the 2025 regular season, the Ragin’ Cajuns have accumulated 56 points, placing them 68th in the nation for scoring offense. Their rushing attack has been more effective, ranking 36th with 583 yards. However, the passing game needs work as they rank 160th with only 178 passing yards.

Offensive Leaders

Running backs Zylan Perry and Bill Davis have been instrumental in the Ragin’ Cajuns’ offensive schemes. Perry leads the team with 226 rushing yards, while Davis follows closely with 191 rushing yards and two touchdowns.

Quarterback Daniel Beale has struggled to establish a rhythm in the passing game. With only 91 passing yards over three games, the Ragin’ Cajuns need more consistency from their signal-caller.

Defensive Insights

Defensively, the Ragin’ Cajuns have allowed 76 points, placing them 61st in the nation. Their pass defense has shown promise, ranking 3rd in interceptions with two.

The team has also excelled in pressuring opposing quarterbacks, tallying five sacks, which is ranked 10th nationally. They need to maintain this level of defensive intensity to remain competitive in their upcoming contests.

Previous Game Recap

In their recent game against Missouri, the Ragin’ Cajuns struggled both offensively and defensively. They managed only 4 passing yards and 117 rushing yards, compared to Missouri’s dominant 427 rushing yards.

The lack of offensive production resulted in only four first downs throughout the game, highlighting their struggles against tougher competition. Moving forward, they will need to enhance their offensive efficiency to succeed.

Betting Trends

  • ATS – After Loss: 10-1 (90.9%) in last 11 games
  • SU – Away Games: 6-1 (85.7%) in last 7 games
  • SU – As Favorite: 21-9 (70.0%) in last 30 games
  • O/U – Away Games: 14-7 (66.7%) in last 21 games
  • ATS – Away Games: 6-2 (75.0%) in last 8 games

Eastern Michigan vs Louisiana-Lafayette Prediction: Over 51.5

The upcoming game between Eastern Michigan and Louisiana-Lafayette is set to be an intriguing matchup with a high potential for scoring. Eastern Michigan has shown a tendency to go over the total at home, hitting the over in 6 of their last 8 home games. Considering their recent high-scoring game against Kentucky, where they lost 48-23, there’s a good chance we’ll see a continuation of this trend.

Louisiana-Lafayette, despite their 1-2 record, has demonstrated offensive capabilities, particularly with their running game ranking 36th nationally. The Ragin’ Cajuns have scored a total of 56 points this season and will likely exploit Eastern Michigan’s defense, which has allowed 128 points so far. This sets the stage for a high-scoring affair.

Given the offensive potential from both teams and their respective defensive struggles, betting the over appears to be the logical choice. With Eastern Michigan’s offensive output at home and Louisiana-Lafayette’s ability to score on the ground, expect the game to exceed the 51.5-point total. A projected scoreline of 35-28 in favor of Louisiana-Lafayette supports this pick.

Both teams have shown vulnerabilities on defense and strengths in specific offensive areas, which should lead to a dynamic game. With these factors in mind, taking the over seems to be the prudent play for this matchup.

  • Eastern Michigan vs Louisiana-Lafayette Prediction: Over 51.5
  • Eastern Michigan vs Louisiana-Lafayette Score: Louisiana-Lafayette 35 – Eastern Michigan 28
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