NFL Game Prediction

Colts vs Titans Prediction & Betting Tips for NFL Week 8 on 10/26/2025

Want our best Colts vs Titans prediction for NFL week 8 on 10/26/25? Get our NFL betting tip as the Tennessee Titans travel to the Indianapolis Colts on 10/26/25 at Lucas Oil Stadium, in Indianapolis. Knup Sports has your free pick!

In Week 8 of the 2025 NFL season, the Tennessee Titans travel to face the Indianapolis Colts at Lucas Oil Stadium. With a retractable roof, weather conditions are expected to be mild and overcast, minimizing any weather-related impact on the game. The game will be broadcast on CBS at 4:25 PM on Sunday, October 26, 2025.

The Titans, under interim head coach Mike McCoy, have struggled with a 1-6 record this season. Their recent losses against the New England Patriots and Las Vegas Raiders have highlighted challenges on both sides of the ball. Despite these setbacks, a previous win against the Arizona Cardinals offers a glimpse of potential.

The Colts, led by head coach Shane Steichen, have been dominant with a 6-1 record, including a perfect home record at Lucas Oil Stadium. Recent victories against the Los Angeles Chargers and Arizona Cardinals have showcased their offensive and defensive strengths. Their earlier win over the Titans in Week 3 with a score of 41-20 will likely boost their confidence heading into this game.

Colts vs Titans At a Glance

  • Game Location: Lucas Oil Stadium in Indianapolis, IN
  • Weather Forecast: Overcast clouds with mild conditions and a light breeze
  • TV Broadcast: CBS
  • Titans Current Record: 1-6-0
  • Colts Current Record: 6-1-0
  • Game Odds: Colts favored at -1203 with a spread of -14.0

Colts Look to Continue Winning Streak Against Tennessee Titans

Colts Offensive Overview

The Indianapolis Colts have had a balanced offensive performance this season, ranking 16th in scoring with 377 points. Their rushing attack, led by Jonathan Taylor, stands out with 2,331 rushing yards, placing them 8th in the league. Passing yards have been a weaker area, ranking 25th with 3,361 yards.

Quarterback Daniel Jones has contributed significantly with 1,790 passing yards and 10 touchdowns, ranking him 5th in the league for passing yards. Taylor has been a dominant force, leading the league with 697 rushing yards and 10 touchdowns. His consistency in the run game is vital for the Colts’ success.

Defensive Performance

Defensively, the Colts have been competitive, ranking 13th in sacks with 36 and 4th in interceptions with 16. Their ability to recover fumbles is also noteworthy, ranking 5th with 10 recoveries.

However, the defense has allowed 6,140 opponent offensive yards, ranking them 29th. Despite this, their ability to create turnovers has been a crucial factor in securing victories.

Key Players to Watch

Jonathan Taylor continues to be a key player for the Colts, leading the team in rushing and providing versatility with 23 receptions. Tyler Warren has been a reliable target in the passing game, contributing 439 receiving yards and 3 touchdowns.

On the defensive side, DeForest Buckner and Nick Cross have been standouts. Buckner leads with 4 sacks, while Cross has made significant contributions with 1 interception in recent games.

Recent Game Performances

The Colts have shown resilience in recent games, winning 4 of their last 5 contests. Their most impressive victory came against the Los Angeles Chargers, where they secured a 38-24 win.

In their last outing against the Arizona Cardinals, the Colts managed a close 31-27 victory. Consistent performances from Taylor and Jones have been pivotal in these wins.

Indianapolis Colts Top Betting Trends

  • SU – Home Games (REG): Last 6 REG Games (2024–2025) → 6-0 (100.0%)
  • SU – As Favorite (REG): Last 5 REG Games (2024–2025) → 5-0 (100.0%)
  • SU – After Loss (REG): Last 5 REG Games (2024–2025) → 5-0 (100.0%)
  • ATS – After Loss (REG): Last 4 REG Games (2024–2025) → 4-0 (100.0%)
  • SU – All Games (REG): Last 8 REG Games (2024–2025) → 7-1 (87.5%)
  • O/U – Away Games (REG): Last 7 REG Games (2024–2025) → 6-1 (85.7%)
  • O/U – All Games (REG): Last 15 REG Games (2024–2025) → 11-4 (73.3%)

Tennessee Titans: A Challenging Road Ahead Against the Colts

Team Overview

The Tennessee Titans have had a difficult 2025 season, currently holding a 1-2 record over their last three games. Their offense has struggled, ranking 25th in scoring and 26th in passing yards during the 2024 season. With a challenging matchup against the Indianapolis Colts on the horizon, the Titans face a crucial test.

Offensively, the Titans have relied heavily on Cameron Ward, who has thrown for 1,356 yards in seven games. However, his performance has been hindered by interceptions, ranking 33rd with five thrown this season. The team will need him to limit turnovers if they hope to compete against the Colts.

Offensive Players to Watch

Tony Pollard has been a key contributor in the backfield, rushing for 380 yards and scoring two touchdowns this season. Despite his efforts, the Titans’ rushing attack ranks only 19th, putting more pressure on Pollard to perform against a stout Colts defense.

Calvin Ridley leads the Titans’ receiving corps with 290 yards, despite missing one game. His status is questionable due to a hamstring injury, and his availability could significantly impact the Titans’ passing game.

Defensive Challenges

The Titans’ defense ranks 27th in opponent scoring, allowing 460 points last season. Although they have been effective at creating turnovers, with 11 interceptions and six fumbles recovered, their inability to consistently stop opponents has been costly.

Jeffery Simmons, a key defensive lineman, is questionable for the upcoming game due to a hamstring injury. His presence on the field is crucial for Tennessee’s pass rush, which ranks 16th with 32 sacks last season.

Team Betting Trends

  • O/U – Home Games (REG): Last 5 REG Games (2024–2025) → 5-0 (100.0%)
  • O/U – As Underdog (REG): Last 11 REG Games (2024–2025) → 8-3 (72.7%)
  • O/U – After Loss (REG): Last 5 REG Games (2025) → 4-1 (80.0%)
  • O/U – All Games (REG): Last 14 REG Games (2024–2025) → 9-5 (64.3%)
  • O/U – Totals ≤ 42 (REG): Last 6 REG Games (2024–2025) → 4-2 (66.7%)
  • O/U – Away Games (REG): Last 8 REG Games (2024–2025) → 4-4 (50.0%)
  • ATS – Away Games (REG): Last 4 REG Games (2025) → 2-2 (50.0%)
  • ATS – After Loss (REG): Last 6 REG Games (2025) → 2-4 (33.3%)

Injury Concerns

The Titans have several players on the injury list, including key starters like Calvin Ridley and Jeffery Simmons. With these crucial players potentially sidelined, Tennessee’s depth will be tested against a strong Colts team.

Will Levis and Mike Brown are confirmed out, further impacting the Titans’ roster depth. As they head into Week 8, the Titans need to find ways to compensate for these absences.

Colts vs Titans Prediction: Colts -14.0

The Indianapolis Colts have been dominant at home this season with a perfect 4-0 record. Against a struggling Tennessee Titans team, who are 1-6 overall and 1-3 on the road, the Colts have a significant advantage. The Colts have also covered the spread in five of their last six home games, showcasing their consistency in performing against the spread (ATS).

Despite the Titans’ interim head coach Mike McCoy’s efforts, the team has faced challenges, evident in their poor season record. With the Colts’ strong offensive showing, ranking 16th in scoring last season, they are well-positioned to exploit the Titans’ defensive weaknesses. The Titans’ defense ranked 27th in opponent scoring last season, which could spell trouble against the Colts’ efficient offense.

The head-to-head history favors Indianapolis, having won their last three encounters against the Titans. The Colts’ robust performance in divisional games, including a recent 41-20 victory over the Titans, further solidifies their chances of covering the spread. Given the Colts’ strong performance metrics and historical dominance, taking them at -14.0 appears a sound choice.

While the total is set at 47.0, the Colts’ offensive might and the Titans’ defensive struggles could push the game towards a higher total. The Colts are expected to score efficiently while limiting the Titans’ offensive opportunities. Projecting a final score of Colts 38 – Titans 17 aligns with this analysis.

  • Colts vs Titans Prediction: Colts -14.0
  • Colts vs Titans Score: Colts 38 – Titans 17
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