In Week 4 of the 2025 regular season, the Syracuse Orange travel to Memorial Stadium in Clemson, SC, for an Atlantic Coast Conference showdown against the Clemson Tigers. This Saturday afternoon game is set to kick off at 12:00 PM and will be broadcast on ESPN. Both teams look to make their mark early in conference play.
The Syracuse Orange enter this contest with a 2-1 record, coming off a decisive 66-24 victory over the Colgate Raiders. They have yet to play a road game this season, making this their first test away from the JMA Wireless Dome. Syracuse aims to carry over its potent offensive display from their recent outings as they face a challenging Clemson defense.
Clemson, holding a 1-2 record, seeks to bounce back after a narrow 24-21 loss to Georgia Tech. With a 1-1 home record, the Tigers will leverage the familiar surroundings of Memorial Stadium to regain their footing. The odds favor Clemson significantly, with a spread of -17.5, but they will need to execute effectively on both sides of the ball to secure a win.
Clemson vs Syracuse At a Glance
- Game Date and Time: Saturday, September 20, 2025 at 12:00 PM
- Venue: Memorial Stadium in Clemson, SC
- TV Channel: ESPN
- Clemson Tigers Record: 1-2 overall, 1-1 at home
- Syracuse Orange Record: 2-1 overall, 0-0 on the road
- Game Odds: Syracuse +566, Clemson -840 (Moneyline); Clemson -17.5 spread
Clemson Tigers Seek Redemption After Georgia Tech Defeat
Offensive Struggles
The Clemson Tigers have found themselves grappling with offensive consistency this season. Currently, their overall offensive production ranks in the middle of the pack nationally, with a points-for total of 58, placing them at 66th. Their passing game has managed to accumulate 633 yards, which is ranked 73rd, while the rushing attack is struggling at 326 yards, placing them at 106th.
A closer look at the individual performances shows quarterback Cade Klubnik leading the charge with 633 passing yards and three touchdowns. On the ground, running back Adam Randall has contributed 208 rushing yards, with three touchdowns. Despite these efforts, the Tigers will need a more balanced offensive attack to improve their standing.
Defensive Bright Spots
Clemson’s defense has shown promise, ranking 9th in the nation with six sacks, demonstrating their ability to pressure opposing quarterbacks effectively. Their secondary has been equally impressive, ranking 4th with three interceptions. This defensive prowess will be crucial as they look to contain their future opponents.
The Tigers’ ability to force turnovers has been a positive aspect, with two fumbles recovered, also ranking 4th nationally. Maintaining this defensive intensity could be key to turning their season around. However, they must find ways to translate these defensive efforts into more wins.
Recent Performance Recap
Clemson’s recent games have been a mixed bag, starting with a narrow 17-10 loss to LSU. The Tigers then secured a victory over Troy, with a 27-16 win at home. However, they stumbled again against Georgia Tech, losing 24-21 in a closely contested game.
In these games, Clemson’s performance has been inconsistent, particularly on offense, where they have struggled to sustain drives and convert opportunities into points. To improve their prospects, the Tigers need to find a rhythm and minimize costly turnovers, like the interception thrown against Georgia Tech.
Key Players to Watch
Wide receiver Bryant Wesco Jr. has been a standout performer with 18 receptions for 310 yards and three touchdowns. His ability to make plays down the field could be pivotal in opening up the offense. Additionally, kicker Nolan Hauser has been reliable, with three field goals and seven extra points made, ensuring the Tigers capitalize on their scoring opportunities.
Despite these individual contributions, Clemson’s success will hinge on how well they can execute as a unit. The pressure is on for both the offense and defense to step up and deliver consistent performances in the coming weeks.
Betting Trends
- SU – After Loss: 10-0 (100.0%)
- SU – Home Games: 24-4 (85.7%)
- SU – Totals ≥ 50: 25-5 (83.3%)
- SU – All Games: 19-6 (76.0%)
- SU – As Favorite: 17-5 (77.3%)
- SU – Away Games: 18-6 (75.0%)
- SU – After Win: 21-9 (70.0%)
- ATS – After Loss: 7-2 (77.8%)
- ATS – Away Games: 14-9 (60.9%)
- O/U – Home Games: 14-10-1 (56.0%)
- O/U – After Loss: 4-2 (66.7%)
- ATS – Totals ≥ 50: 14-13 (51.9%)
Syracuse Orange: A Deep Dive into Their Upcoming Game
Offensive Performance
Syracuse Orange’s offense has been impressive this season, ranking 3rd in passing yards with 1138 yards. However, their rushing game lags behind, placing 107th with only 322 yards. This disparity emphasizes a reliance on aerial attacks.
In their last game against Colgate, the Orange put up 66 points, showcasing their ability to capitalize on weaker defenses. They managed to accumulate 447 passing yards, which again underscores their strength in the air.
Defensive Statistics
Defensively, Syracuse has allowed 89 points this season, ranking them 72nd. Their defense has managed to secure 3 sacks, placing them at 12th, while their interception skills are notable with 2, ranking 3rd.
Despite their strength in interceptions, their overall defensive ranking indicates room for improvement. Their ability to recover fumbles also stands out, ranking 5th with one recovery this season.
Key Players
Quarterback Steve Angeli has been a pivotal player, leading the league with 1108 passing yards and ranking first in the team for passing touchdowns. His performance is crucial for Syracuse’s continued success.
On the receiving end, Darrell Gill Jr. has been a standout with 269 receiving yards, ranking 26th in the league. His ability to make significant plays downfield complements Angeli’s passing prowess.
Upcoming Challenges
Facing the Clemson Tigers, Syracuse will need to rely heavily on their passing game. The Tigers are known for their strong defense, which will test Syracuse’s offensive capabilities.
With key players like Mark Petry out due to injuries, the Orange will have to adapt and find ways to fill these gaps. Their ability to strategize around these challenges will be crucial in their upcoming game.
Betting Trends
- SU – As Favorite: 18-1 in their last 19 games (94.7%)
- O/U – All Games: 5-0-1 in their last 6 games (83.3%)
- O/U – Totals ≥ 50: 5-0-1 in their last 6 games (83.3%)
- O/U – As Underdog: 3-0-1 in their last 4 games (75.0%)
- O/U – After Win: 3-0 in their last 3 games (100.0%)
Clemson vs Syracuse Prediction: Over 55.5
Heading into this Week 4 matchup, the Clemson Tigers are set to take on the Syracuse Orange at Memorial Stadium. Clemson, although struggling early this season with a 1-2 record, is looking to bounce back on their home turf where they have been quite successful historically. The over/under is set at 55.5, and with both teams having shown offensive capabilities, the over looks appealing.
Syracuse has been formidable on offense, scoring 119 points in just three games this season, ranking them 21st nationally. Their passing game has been particularly potent, as they rank 3rd in the nation in passing yards. This offensive firepower should help propel the game to a higher score, especially against a Clemson team that is often involved in high-scoring affairs.
Clemson’s defense, while usually strong, has allowed 57 points through their first three games. Coupled with Syracuse’s offensive capabilities, this could lead to a competitive and high-scoring game. Historical matchups between these two teams have seen lower scores, but this season’s trends suggest a shift towards a higher-scoring battle.
The betting trends for Clemson also suggest a tendency for higher totals in home games, with a 56% over rate in their last 25 home games. The combination of Syracuse’s offensive ranking and Clemson’s defensive lapses point towards a game that could easily surpass the current total line of 55.5.
- Clemson vs Syracuse Prediction: Over 55.5
- Clemson vs Syracuse Score: Clemson 38 – Syracuse 24
