The Indianapolis Colts will travel to SoFi Stadium to take on the Los Angeles Chargers in a Week 7 NFL game. The Colts, led by head coach Shane Steichen, enter the contest with a strong 5-1-0 record and a balanced performance both at home and on the road. Meanwhile, the Chargers, coached by Jim Harbaugh, boast a 4-2-0 record and have shown resilience at home with a 2-1-0 record.
This game is scheduled for Sunday, October 19, 2025, at 4:05 PM and will be broadcast on CBS. While weather conditions are generally not a concern for a dome stadium like SoFi, the Colts will look to extend their winning streak after their recent 31-27 victory against the Arizona Cardinals. On the other hand, the Chargers aim to build on their momentum following a narrow 29-27 win over the Miami Dolphins.
The betting odds slightly favor the Chargers with a moneyline of -130, while the Colts stand at +109. The consensus spread is set at +1.5 for the Colts and -1.5 for the Chargers, indicating a closely contested game. With both teams having dynamic offenses and solid defenses, fans can expect a competitive matchup in Inglewood.
Chargers vs Colts At a Glance
- Game Date & Time: Sunday, October 19, 2025, at 4:05 PM.
- Location: SoFi Stadium in Inglewood, CA — Dome.
- TV Broadcast: CBS.
- Indianapolis Colts Record: 5-1-0 overall, 1-1-0 on the road.
- Los Angeles Chargers Record: 4-2-0 overall, 2-1-0 at home.
- Game Odds: Chargers favored with a moneyline of -130; Colts at +109.
Explosive Chargers Ready to Electrify Their Opponents
Offensive Analysis
The Los Angeles Chargers’ offense ranks 11th in scoring with 402 points, demonstrating a potent ability to find the end zone. Their passing game, led by Justin Herbert, recorded 3,629 yards and ranks 19th, indicating room for improvement. In the rushing department, the Chargers accumulated 1,882 yards, securing the 17th spot in the league.
The Chargers’ offense is adept at converting on third downs, achieving a 40.3% success rate, which ranks them 11th. They have managed to secure 316 first downs, placing them 18th overall. These figures underscore their ability to sustain drives and keep the chains moving.
Defensive Standouts
Defensively, the Chargers shine, leading the league by allowing just 301 points. Their pass rush has been impressive with 46 sacks, ranking 5th in the league. The Chargers’ defense has also proven opportunistic, with 15 interceptions, tying them for 5th place.
They rank 9th in fumbles recovered with 6, showcasing their knack for taking advantage of opponents’ mistakes. The Chargers’ defense holds opponents to 5,514 offensive yards, earning them an 11th place rank. This solid defensive performance is a key factor in their overall success.
Key Players and Recent Performances
Justin Herbert remains the cornerstone of the Chargers’ offense, with 1,493 passing yards and 10 touchdowns this season. He ranks 8th in passing yards and 9th in passing touchdowns, highlighting his consistent performance. On the ground, Omarion Hampton leads with 314 rushing yards and 2 touchdowns.
Quentin Johnston is a vital target, with 377 receiving yards and 4 touchdowns, ranking 17th in receiving yards. The Chargers’ recent win against the Dolphins, 29-27, highlighted their resilience and ability to execute in close games. In that victory, Herbert threw for 264 yards and 2 touchdowns, while Ladd McConkey contributed 100 receiving yards and a touchdown.
Injury Concerns
The Chargers face challenges with several key players on the injured reserve list, impacting their depth. Khalil Mack and Omarion Hampton are notable absentees who will miss significant time. Additionally, Denzel Perryman’s status is questionable, which may impact the linebacking corps.
Najee Harris and Rashawn Slater are out for the season, adding to the Chargers’ injury woes. The team will need to rely on depth players to fill these critical gaps. Ensuring the health of key contributors will be crucial as the Chargers aim for a successful campaign.
Betting Trends
- SU – Totals ≤ 42 (REG): 4-0 (100.0%) in the last 4 games (2024)
- ATS – Totals ≤ 42 (REG): 4-0 (100.0%) in the last 4 games (2024)
- O/U – Totals ≤ 42 (REG): 4-0 (100.0%) in the last 4 games (2024)
- SU – As Favorite (REG): 9-3 (75.0%) in the last 12 games (2024–2025)
- SU – After Win (REG): 5-1 (83.3%) in the last 6 games (2024–2025)
- ATS – After Win (REG): 5-1 (83.3%) in the last 6 games (2024–2025)
Indianapolis Colts Set to Challenge Chargers in Upcoming Game
Colts Offensive Overview
The Indianapolis Colts are entering their upcoming game with a balanced offensive attack. They currently rank 16th in scoring with a total of 377 points, while their rushing game is notably strong, ranking 8th with 2331 rushing yards. The passing game, however, is an area needing improvement as they rank 25th in passing yards with 3361 yards.
Quarterback Daniel Jones has been a central figure in the Colts’ offense. He has thrown for 1502 yards, placing him 7th in the league, and has achieved 8 passing touchdowns. Jonathan Taylor, leading the rushing attack, is a key player with 603 rushing yards, making him the league leader in this category.
Defensive Strengths and Weaknesses
The Colts’ defense has been a mix of strengths and vulnerabilities this season. They have excelled in generating turnovers, with 16 opponent passing interceptions, ranking 4th, and 10 fumbles recovered, ranking 5th. Despite these strengths, their overall defensive yardage needs work, as they have allowed 6140 opponent offensive yards, ranking 29th.
Sacks have been a significant part of their defense with 36 sacks, placing them 13th in the league. This pass rush capability is crucial in disrupting opposing quarterbacks and will be vital against the Chargers.
Recent Performances
In recent games, the Colts have shown a mix of results, including a high-scoring victory against the Las Vegas Raiders with a 40-6 score. Their last game saw them secure a 31-27 win over the Arizona Cardinals, showcasing their ability to perform under pressure. However, they faced a setback against the Los Angeles Rams, losing 27-20.
Key offensive players such as Jonathan Taylor and Daniel Jones have consistently contributed to the team’s performance. Taylor’s rushing and receiving abilities, along with Jones’ passing, are central to their offensive strategy.
Injury Concerns
The Colts face significant injury challenges, with several key players on the injured reserve list. Notably, Anthony Richardson Sr. is out with an eye injury, which impacts their quarterback depth. Additionally, Spencer Shrader’s knee injury will keep him out for the remainder of the season, affecting their kicking game.
Defensive depth is also impacted with injuries to players like Mike Hilton and Kenny Moore II, which could challenge their secondary against a strong passing attack like the Chargers.
Colts Betting Trends
- SU – Home Games (REG): Last 6 REG Games (2024–2025) → 6-0 (100.0%)
- SU – As Favorite (REG): Last 5 REG Games (2024–2025) → 5-0 (100.0%)
- SU – After Loss (REG): Last 5 REG Games (2024–2025) → 5-0 (100.0%)
- ATS – After Loss (REG): Last 4 REG Games (2024–2025) → 4-0 (100.0%)
- SU – All Games (REG): Last 7 REG Games (2024–2025) → 6-1 (85.7%)
Chargers vs Colts Prediction: Chargers -1.5
The Los Angeles Chargers come into this game with a 4-2 record and a strong performance as favorites, having gone 9-3 straight up in their last 12 games when favored. Their home performance is also solid, with a 3-1 record against the spread in their last four home games. With the Chargers’ defense ranked first in opponent scoring, they have a strong edge playing at SoFi Stadium.
On the other hand, the Indianapolis Colts have been impressive with a 5-1 start to the season. However, their road performance hasn’t been as dominant, with a 1-1 record. The Colts’ offense, ranking 16th in scoring, may struggle against the Chargers’ top-ranked defense.
The spread is set at -1.5 in favor of the Chargers, and given their recent trends and strong home performance, this seems like a favorable pick. The Colts might pose a challenge, but the Chargers’ defensive prowess should give them the edge.
For the total points, the line is set at 48.5. Considering the Chargers’ defensive strength and the Colts’ average offensive ranking, a lower-scoring game could be anticipated, but the main focus remains on the Chargers covering the spread.
- Chargers vs Colts Prediction: Chargers -1.5
- Chargers vs Colts Score: Chargers 24 – Colts 20
