MLB Game Prediction

Boston Red Sox vs New York Yankees Prediction & Betting Tips for 9/12/2025

Want our best Boston Red Sox vs New York Yankees prediction for 9/12/25? Get our MLB betting tip as the Yankees travel to the Red Sox on 9/12/25 at Fenway Park, in Boston. Knup Sports has your free pick!

The New York Yankees are set to take on the Boston Red Sox at Fenway Park on Friday, September 12, 2025, at 7:10 PM. The Yankees, managed by Aaron Boone, hold a record of 81-65 and currently rank 2nd in the AL East. Having recently triumphed 9-3 against the Detroit Tigers, the Yankees come into this game with a positive note.

The Red Sox, led by manager Alex Cora, are closely trailing the Yankees with an 81-66 record and sit in 3rd place in the same division. Despite their recent 5-4 loss to the Athletics, the Red Sox have shown strong form, winning six of their last ten games. The outdoor setting of Fenway Park and clear skies are expected to provide an ideal backdrop for this highly anticipated game.

Both teams are evenly matched, with the Yankees’ road record standing at 37-34 and the Red Sox’s home record at 44-28. The sportsbooks have the Yankees as slight favorites with a moneyline of -123 compared to the Red Sox at +103. With both teams vying for a higher spot in the division standings, this game holds significant implications for the playoff race.

Red Sox vs Yankees At a Glance

  • Game Date: Friday, September 12, 2025 at 7:10 PM
  • Stadium: Fenway Park in Boston, MA
  • Weather Forecast: Clear sky with a mild day and light breeze
  • TV Channel: APLTV
  • Yankees Record: 81-65, 2nd in AL East
  • Red Sox Record: 81-66, 3rd in AL East

Red Sox Look to Stay Hot Against Yankees

Yankees Hitting Overview

The Yankees have been effective at the plate, with a batting average of .254, ranking 4th in the league. Their on-base percentage of .323 positions them 6th, highlighting their ability to get runners on base. The team is also 7th in slugging percentage, indicating a balanced offensive threat.

The Yankees have shown power with 173 home runs this season, placing them 10th overall. Their impressive tally of 300 doubles leads the league, showcasing their ability to hit for extra bases. This combination of power and contact makes them a formidable opponent.

Yankees Key Players to Watch

New York’s offensive depth is evident with players contributing across various metrics. A standout performer for the Yankees is their ability to work counts and draw walks, with 470 walks ranking 12th in the league. This patience at the plate will be a key factor in their matchup against the Red Sox.

The Yankees’ speed on the bases is also a threat, with 125 stolen bases, ranking them 6th in the league. Their aggressive baserunning could create additional scoring opportunities. However, they must be cautious, as their 1293 strikeouts rank 24th, indicating susceptibility to high strikeout pitchers.

Yankees Pitching Insights

On the mound, the Yankees boast a strong earned run average (ERA) of 3.74, ranking them 5th in the league. Their pitching staff has been effective in limiting home runs, allowing only 150, which is also 5th best in the league. This ability to prevent the long ball will be crucial against a power-hitting Red Sox lineup.

Yankees pitchers have delivered 67 quality starts, ranking them 2nd, demonstrating their consistency and ability to keep the team in games. With 1218 strikeouts, they rank 16th, showing a balance between overpowering hitters and maintaining control on the mound.

Yankees Team Betting Trends

  • SU All Games: 81-66 (55.1%)
  • SU as Favorite: 54-39 (58.1%)
  • SU as Underdog: 27-27 (50.0%)
  • SU in Away Games: 37-38 (49.3%)
  • Runline All Games: 78-69 (53.1%)
  • Runline as Underdog: 33-21 (61.1%)
  • O/U All Games: 71-76 (48.3%)
  • O/U in Away Games: 39-36 (52.0%)

The Yankees Take on the Red Sox: A Fenway Park Showdown

Red Sox Hitting Overview

The Boston Red Sox lineup has shown impressive depth this season, with their batting average standing at a competitive .249, ranking them 8th in the league. Their on-base percentage of .329 ranks even higher at 3rd, indicating a disciplined approach at the plate. Moreover, their power is evident in a league-leading slugging percentage of .455 and a commanding 249 home runs, which also tops the league.

However, the team is not without weaknesses, as seen in their 12th place ranking in doubles with 230. Despite this, their ability to draw walks and avoid strikeouts is noteworthy. They have collected 569 walks, the highest in the league, while managing to keep strikeouts relatively low at 1302, ranking them 27th.

Red Sox Pitching Insights

On the pitching side, the Red Sox maintain an earned run average (ERA) of 4.01, placing them 16th. This is complemented by a strong batting average against (BAA) of .231, which ranks 4th, showcasing their effectiveness in limiting opponent hits. They have given up 158 home runs, putting them in the middle of the pack at 12th place.

Their pitching staff has delivered 54 quality starts, ranking 10th, demonstrating their ability to provide consistent innings. However, the bullpen has had its challenges, with 21 blown saves ranking 5th. Despite this, their pitchers have amassed 1295 strikeouts, placing them 4th in the league, highlighting their ability to overpower hitters.

Key Red Sox Players to Watch

The Red Sox lineup is powered by several standout performers. Their home run and RBI leader Trent Grisham, with 30 home runs and 64 RBIs, poses a significant threat. Additionally, Cody Bellinger contributes significantly with a .277 average and 90 RBIs.

In the rotation, Lucas Giolito has been a key contributor, boasting a 3.38 ERA and a 10-3 record. His ability to limit baserunners, as indicated by his 1.26 WHIP, will be crucial against the Yankees’ potent lineup.

Red Sox Betting Trends

  • SU Last 3 Games: 1-2 (33.3%)
  • SU Last 5 Games: 3-2 (60.0%)
  • SU Last 10 Games: 5-5 (50.0%)
  • SU All Games: 81-65 (55.5%)
  • SU as Favorite: 73-53 (57.9%)
  • SU as Underdog: 8-12 (40.0%)
  • SU in Night Games: 51-43 (54.3%)
  • SU in Day Games: 30-22 (57.7%)
  • SU in Home Games: 44-31 (58.7%)
  • SU in Away Games: 37-34 (52.1%)
  • SU vs Division Opponents: 28-32 (46.7%)
  • SU vs League Opponents: 36-20 (64.3%)
  • SU in 1-Run Games: 20-22 (47.6%)
  • SU After a Win: 45-35 (56.2%)
  • SU After a Loss: 35-30 (53.8%)

Red Sox vs Yankees Prediction: Red Sox +103

The Boston Red Sox host the New York Yankees at Fenway Park in what promises to be a significant late-season series for both teams. The Red Sox come into the game with a home record of 44-28, showing their strength at Fenway. Given the close odds and the Red Sox’s slightly better recent form, taking them at +103 offers value.

Boston’s Lucas Giolito, with a 10-3 record and a respectable 3.38 ERA, will be on the mound. Giolito’s experience and consistency provide an edge over New York’s Luis Gil, whose WHIP of 1.53 could pose challenges against a potent Boston lineup. The Red Sox’s ability to win close games at home further supports the decision to back them.

While both teams have similar records, Boston has dominated their recent head-to-head encounters, winning 8 of the last 10 meetings. Their robust division record of 27-16 this season also suggests they have what it takes to overcome the Yankees in this game.

Given the Red Sox’s home strength, Giolito’s pitching, and their favorable head-to-head record, a projected scoreline of Red Sox 4 – Yankees 3 is anticipated. This supports the pick of Boston at plus odds for this matchup.

  • Red Sox vs Yankees Prediction: Red Sox +103
  • Red Sox vs Yankees Score: Red Sox 4 – Yankees 3
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