MLB Game Prediction

Milwaukee Brewers vs Chicago Cubs Prediction & Betting Tips for NLDS 2 on 10/6/2025

Want our best Milwaukee Brewers vs Chicago Cubs prediction for NLDS 2 on 10/6/25? Get our MLB betting tip as the Cubs travel to the Brewers on 10/6/25 at American Family Field, in Milwaukee. Knup Sports has your free pick!

The Milwaukee Brewers take on the Chicago Cubs in Game 2 of the National League Division Series. Currently leading the series 1-0, the Brewers will host the Cubs at American Family Field in Milwaukee. The game is scheduled for a night start at 9:08 PM on October 6, 2025, and will be broadcast on TBS.

The Cubs, managed by Craig Counsell, finished the regular season with a 92-70 record. Despite a recent loss to the Brewers, they remain determined to bounce back with their road record of 42-39. Their recent performance against the Padres in the postseason shows their potential to recover quickly.

The Brewers, under manager Pat Murphy, hold a strong regular season record of 97-65. With a home record of 52-29, they aim to capitalize on their home advantage. Their recent victory over the Cubs, with standout performances from players like Jackson Chourio, sets a positive tone for Game 2.

Brewers vs Cubs NLDS 2 At a Glance

  • Game Context: This is Game 2 of the NLDS with the Brewers leading the series 1-0.
  • Venue Details: The game takes place at American Family Field in Milwaukee, WI, which has a retractable roof.
  • Television Coverage: Fans can catch the action live on TBS.
  • Weather Conditions: Expect mild temperatures with a light breeze, and conditions are described as ‘Light Rain’.
  • Team Performance: The Brewers ended their regular season with a 97-65 record, while the Cubs had a 92-70 record.
  • Betting Odds: The Brewers are favored with a moneyline of -121, while the Cubs stand at +103.

Brewers Aim to Continue Strong Postseason Run Against Cubs

Offensive Strengths

The Brewers’ lineup has been one of the most effective in the league, ranking second in batting average (.258) and on-base percentage (.331). Their ability to get on base consistently sets them up well for postseason success.

Despite ranking lower in home runs, the Brewers have shown they can score runs through other means, leading the league in unearned runs this season. Their focus on small-ball tactics has been effective, with a high number of doubles and stolen bases.

Key Offensive Players

Brice Turang has been a standout performer for Milwaukee, posting a .288 batting average and leading the team in home runs and RBIs among position players. His consistency at the plate is vital for the Brewers’ offensive engine.

William Contreras, while not leading in power stats, provides a solid presence behind the plate and contributes significantly to run production with a .260 batting average and 76 RBIs. His ability to get on base frequently makes him a crucial part of the lineup.

Pitching Prowess

The Brewers’ pitching staff has been a cornerstone of their success, with a 3.59 ERA ranking second in the league. They have been effective at limiting opposing batters, evidenced by their .230 batting average against.

Aaron Ashby will take the mound for Game 2, coming off a season where he finished with a 2.16 ERA. His ability to limit runs and keep batters off balance will be key in maintaining the Brewers’ advantage.

Defensive and Strategic Considerations

Defensively, Milwaukee has been solid, with a disciplined approach that minimizes errors. Their ability to convert defensive plays into outs has been a strength, helping to support their strong pitching performances.

Manager Pat Murphy’s strategic decisions, such as using Ashby as an opener, show a willingness to adapt and maximize the effectiveness of his pitching staff. This flexibility could be advantageous as the series progresses.

Betting Trends

  • SU Last 3 Games: 1-0 (100.0%)
  • SU as Favorite: 1-0 (100.0%)
  • Runline in Home Games: 1-0 (100.0%)
  • O/U All Games: 1-0 (100.0%)

Overall, the Brewers’ combination of consistent hitting, strategic pitching, and effective defense positions them well against the Cubs. As they continue their postseason journey, maintaining these strengths will be crucial for their success.

Cubs Ready to Roar: A Look at the Cubs’ Upcoming Game

Overview of the Away Team

The Chicago Cubs are set to play against the Milwaukee Brewers, aiming to turn the tide after a recent loss. The Cubs, playing away at American Family Field, are facing a significant challenge as they aim to even the series.

Despite the setback in Game 1, where they fell 9-3, the Cubs’ lineup remains potent with hitters capable of delivering big performances. Key players like Michael Busch and Nico Hoerner have shown their ability to contribute crucial hits, as seen in previous games.

Key Players to Watch

Seiya Suzuki has been a consistent performer for the Cubs, with a .245 batting average and 32 home runs this season. As the designated hitter, Suzuki’s power at the plate will be crucial in giving the Cubs an offensive edge.

Another player to watch is Michael Busch, who leads the team with 34 home runs. His ability to set the tone early, as demonstrated by his leadoff home run in Game 1, could be pivotal for the Cubs’ success.

Pitching Concerns

The Cubs’ pitching rotation has faced scrutiny, particularly with Shota Imanaga set to start in Game 2. Imanaga has shown resilience, though his tendency to give up home runs is a concern against the Brewers’ lineup.

Imanaga’s performance is critical, especially after the Cubs’ pitching struggles in Game 1. His ability to keep the Brewers’ hitters at bay will be a key factor in the Cubs’ chances of securing a win.

Offensive Strategy

With players like Nico Hoerner and Ian Happ in the lineup, the Cubs will need to focus on creating scoring opportunities beyond relying solely on home runs. Both have demonstrated their capacity to drive in runs and maintain pressure on opposing pitchers.

Dansby Swanson, with his .244 batting average, also adds depth to the Cubs’ offense. His role in the middle of the lineup could be crucial in generating runs and keeping the Cubs competitive throughout the game.

Team Betting Trends

  • SU After a Loss: 2-0 (100.0%)
  • Runline After a Loss: 2-0 (100.0%)
  • O/U in Away Games: 1-0 (100.0%)
  • Runline as Favorite: 2-1 (66.7%)
  • SU in Home Games: 2-1 (66.7%)

These betting trends highlight the Cubs’ resilience and ability to bounce back after a loss, a trait that could prove beneficial in the upcoming game.

Brewers vs Cubs Prediction: Brewers -121

The Milwaukee Brewers enter Game 2 of the NLDS with momentum on their side, having decisively taken Game 1 with a 9-3 victory over the Chicago Cubs. Aaron Ashby’s strong season performance, boasting a 2.16 ERA, and the Brewers’ superior regular-season home record of 52-29, strengthens their case as the favorite with odds of -121. The Brewers’ recent postseason success and the Cubs’ offensive struggles give Milwaukee a significant edge.

Chicago Cubs’ starting pitcher Shota Imanaga has shown inconsistency, with a 4.70 ERA in the second half of the season and a troubling tendency to allow home runs. This vulnerability could be exploited by the Brewers’ lineup, which has demonstrated the ability to score early and often. With the Cubs’ offensive woes, scoring just nine runs across four postseason games, Milwaukee has the upper hand.

Jackson Chourio’s uncertain status due to a hamstring injury is a concern for the Brewers, but their depth, as evidenced by their capability to win without him in the past, remains a strong point. Milwaukee’s strategic advantage lies in their ability to capitalize on the Cubs’ defensive mistakes, as demonstrated by their leading total of unearned runs this season.

The Cubs’ lack of offensive production, coupled with Milwaukee’s effective pitching and home field advantage, suggests that the Brewers are likely to take a commanding 2-0 lead in the series. Anticipate a final score that reflects their dominance in Game 1, projecting a 6-2 victory for the Brewers.

  • Brewers vs Cubs Prediction: Brewers -121
  • Brewers vs Cubs Score: Brewers 6 – Cubs 2
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