NFL Game Prediction

Chargers vs Commanders Prediction & Betting Tips for NFL Week 5 on 10/5/2025

Want our best Chargers vs Commanders prediction for NFL week 5 on 10/5/25? Get our NFL betting tip as the Washington Commanders travel to the Los Angeles Chargers on 10/5/25 at SoFi Stadium, in Los Angeles. Knup Sports has your free pick!

The Washington Commanders will visit the Los Angeles Chargers in Week 5 of the 2025 NFL season. The game will take place at SoFi Stadium in Inglewood, California, a dome venue that negates any potential weather impact. Fans can catch the action live on FOX at 4:25 PM on Sunday, October 5th. Washington, under head coach Dan Quinn, enters this matchup with a 2-2 record. They have struggled on the road, standing at 0-2 away from Northwest Stadium. Their recent performance includes a close 34-27 loss to the Atlanta Falcons in Week 4. The Chargers, led by head coach Jim Harbaugh, hold a 3-1 record and are undefeated at home this season. They will look to bounce back from a narrow 21-18 defeat against the New York Giants. The odds favor the Chargers with a moneyline of -159, while the Commanders stand at +134.

Chargers vs Commanders At a Glance

  • Game Date & Time: Sunday, October 5, 2025 at 4:25 PM
  • Location: SoFi Stadium in Inglewood, CA, USA — Dome
  • Weather: No specific forecast available; being a dome, wind unlikely to impact play
  • TV Channel: FOX
  • Washington Commanders Record: 2-2-0 this season, with a 0-2-0 road record
  • Game Odds: Chargers favored with a moneyline of -159; spread at -3.0 (-106)

Analyzing the Los Angeles Chargers: A Deep Dive into Their Upcoming Game

Offensive Performance Overview

The Los Angeles Chargers’ offense has been performing at a solid level, scoring a total of 402 points in the last regular season, ranking 11th in the league. Their passing attack, led by Justin Herbert, amassed 3,629 yards, placing them 19th. On the ground, the Chargers rushed for 1,882 yards, securing the 17th spot in rushing yards rankings.

First downs have come at a moderate pace for the Chargers, with 316 achieved, ranking 18th. Their third-down conversion rate stands at 40.3%, which is ranked 11th. This efficiency highlights their ability to maintain drives and keep the chains moving.

Defensive Strengths

The Chargers’ defense has been a standout, allowing only 301 points, which is the best in the league. With 46 sacks recorded, they rank 5th, indicating a formidable pass rush. Their secondary has been active, intercepting 15 passes, also ranking 5th in the league.

Fumble recoveries have added to their defensive prowess, with 6 recoveries placing them 9th. The defense has kept opponents to 5,514 total offensive yards, ranking 11th. This consistency is a key factor in their defensive success.

Recent Game Analysis

In their recent game against the New York Giants, the Chargers lost 21-18 despite gaining more passing yards, totaling 186 compared to the Giants’ 89. Omarion Hampton was a bright spot with 128 rushing yards and 1 rushing touchdown. Turnovers proved costly, with Justin Herbert throwing two interceptions.

Against the Denver Broncos, the Chargers secured a 23-20 victory, showcasing their ability to convert first downs with 29 compared to the Broncos’ 9. Justin Herbert threw for 300 yards and a touchdown, while the defense limited the Broncos to just 9 first downs.

Player Spotlight

Justin Herbert has been a key player for the Chargers, ranking 1st on the team with 1,063 passing yards and 7 touchdowns in four games. Omarion Hampton leads the rushing attack with 270 yards and 2 touchdowns. Quentin Johnston and Keenan Allen have been reliable targets, with Johnston leading in receiving yards at 337.

Defensively, Derwin James Jr. and Daiyan Henley have been instrumental in maintaining their top-ranked defense. Daiyan Henley’s performance against the Raiders included a sack and interception, highlighting his playmaking ability.

Injury Concerns

The Chargers are dealing with several key injuries, including Khalil Mack and Rashawn Slater, who are both on injured reserve. Najee Harris is out for the season with an Achilles injury, impacting their depth at running back. Will Dissly and Mekhi Becton are questionable for the upcoming game, which could affect their offensive line and tight end positions.

Upcoming Game and Betting Trends

The Chargers are scheduled to face the Washington Commanders at SoFi Stadium. They enter as 3-point favorites with a total over/under set at 48.0 points. Their strong home performance should give them an edge.

Team Betting Trends

  • SU – Totals ≤ 42 (REG): Last 6 REG Games (2024) → 6-0 (100.0%)
  • ATS – Totals ≤ 42 (REG): Last 6 REG Games (2024) → 6-0 (100.0%)
  • O/U – Totals ≤ 42 (REG): Last 4 REG Games (2024) → 4-0 (100.0%)
  • SU – As Favorite (REG): Last 12 REG Games (2024–2025) → 10-2 (83.3%)
  • ATS – As Favorite (REG): Last 12 REG Games (2024–2025) → 10-2 (83.3%)
  • SU – Home Games (REG): Last 3 REG Games (2024–2025) → 3-0 (100.0%)
  • ATS – Home Games (REG): Last 3 REG Games (2024–2025) → 3-0 (100.0%)
  • SU – All Games (REG): Last 7 REG Games (2024–2025) → 6-1 (85.7%)
  • ATS – All Games (REG): Last 7 REG Games (2024–2025) → 6-1 (85.7%)

Commanders Ready to Challenge Chargers: An In-Depth Analysis

Offensive Performance

The Washington Commanders have showcased a strong offensive presence this season, with a total of 485 points, ranking 5th in the league. Their rushing game has been particularly effective, amassing 2619 yards and securing the 3rd spot in rushing yards. However, their passing game has room for improvement, currently ranked 17th with 3665 yards.

The Commanders’ ability to secure first downs is impressive, with 380 first downs, placing them 4th in the league. Their 45.6% third-down conversion rate also ranks 6th, indicating efficiency in maintaining drives. In recent games, Marcus Mariota has been a crucial part of their offensive strategy, as seen in his performances against Atlanta and Las Vegas.

Defensive Insights

Defensively, the Commanders have allowed 391 points, ranking 17th in the league, which highlights a potential area for improvement. Their defensive line has been effective with 43 sacks, ranking them 7th, showing their ability to pressure opposing quarterbacks. Despite allowing 5558 opponent yards, ranking 13th, they have managed to recover 10 fumbles, standing 5th in the league.

The team has managed to grab 7 interceptions, ranking 12th, which reflects their secondary’s capability to make plays. The recent games showed mixed defensive performances, with varying success in limiting opponents like Green Bay and Atlanta. Key defensive players like Frankie Luvu and Mike Sainristil have been instrumental in these efforts.

Injury Concerns

The Commanders are dealing with several injuries that could impact their performance. Notably, Austin Ekeler and Deatrich Wise Jr. are out for the season, affecting both the offensive and defensive sides. Additionally, critical players like Terry McLaurin and Jayden Daniels are questionable for the upcoming game, which could alter game plans.

The absence of key players, especially on the offensive line and secondary, may challenge the Commanders’ depth. The team will need to rely on their bench strength and strategic adjustments to mitigate these injury challenges.

Recent Game Analysis

The Commanders’ recent games have shown varied outcomes, including a win against the Raiders (41-24) and losses against the Falcons (34-27) and Packers (27-18). In the game against the Falcons, despite a strong rushing performance with 147 yards, they struggled with turnovers, losing 4 fumbles.

Against the Raiders, the Commanders demonstrated offensive balance with 199 passing yards and 201 rushing yards, illustrating their potential when executing effectively. These performances highlight the team’s capability but also the need for consistency and discipline, especially in ball security.

Betting Trends

  • ATS – As Favorite (REG): 11-0 (100.0%) in last 11 games
  • SU – As Favorite (REG): 6-0 (100.0%) in last 6 games
  • SU – Home Games (REG): 5-0 (100.0%) in last 5 games
  • ATS – Home Games (REG): 8-1 (88.9%) in last 9 games
  • ATS – After Loss (REG): 3-0 (100.0%) in last 3 games
  • O/U – After Loss (REG): 3-0 (100.0%) in last 3 games
  • O/U – Home Games (REG): 6-1 (85.7%) in last 7 games
  • ATS – All Games (REG): 11-4 (73.3%) in last 15 games
  • SU – All Games (REG): 7-2 (77.8%) in last 9 games
  • SU – After Win (REG): 7-3 (70.0%) in last 10 games

Chargers vs Commanders Prediction: Over 48.0

The Los Angeles Chargers have shown a consistent ability to score this season, with a 3-1 record and a solid offensive ranking. Playing at home, they are undefeated, and their offense is capable of putting up points against any defense.

The Washington Commanders, while struggling on the road with a 0-2 record, have an offense coordinated by Kliff Kingsbury, known for high-scoring games. Their 2024 season showed a strong offensive output, ranking 5th in scoring.

The historical head-to-head scores between these teams indicate potential for high-scoring games. The Chargers’ trend of hitting the over in 6 out of their last 7 home games further supports an expectation of a high total score.

Considering the offensive capabilities and trends of both teams, the game is poised to exceed the set total of 48.0 points. A projected score of Chargers 31 – Commanders 28 suggests a competitive and high-scoring game.

  • Chargers vs Commanders Prediction: Over 48.0
  • Chargers vs Commanders Score: Chargers 31 – Commanders 28
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