NFL Game Prediction

Saints vs Giants Prediction & Betting Tips for NFL Week 5 on 10/5/2025

Want our best Saints vs Giants prediction for NFL week 5 on 10/5/25? Get our NFL betting tip as the New York Giants travel to the New Orleans Saints on 10/5/25 at Caesars Superdome, in New Orleans. Knup Sports has your free pick!

The New York Giants are heading to the Caesars Superdome to take on the New Orleans Saints in a Week 5 matchup of the 2025 NFL season. The Giants, led by Head Coach Brian Daboll, currently hold a 1-3 record and are looking to build on their recent victory against the Los Angeles Chargers. With a road record of 0-2, they’ll be aiming to secure their first away win of the season. Meanwhile, the Saints are eager to turn their season around under the guidance of Head Coach Kellen Moore. Despite a challenging start with a 0-4 record, they hope to leverage their home-field advantage to claim their first win. The team will rely on the offensive strategies of Coordinator Doug Nussmeier to spark a turnaround. This game, broadcast on CBS, will be played in the enclosed Caesars Superdome, rendering weather conditions irrelevant to the gameplay. The Saints are slight favorites with a spread of -2.0, hinting at a competitive contest between these two NFC teams. Both teams will be looking to make a statement as they strive to improve their standings early in the season.

Saints vs Giants At a Glance

  • Location: Caesars Superdome in New Orleans, LA USA — Dome
  • Game Date and Time: Sunday, October 5, 2025 at 1:00 PM (Afternoon Game)
  • TV Channel: CBS
  • Weather: Temperature and wind conditions not available, dome environment minimizes impact
  • New York Giants Record: 1-3-0 (0-2-0 on the road)
  • New Orleans Saints Record: 0-4-0 (0-2-0 at home)

New Orleans Saints: Analyzing the Team’s Current Form

Recent Performances

The New Orleans Saints have had a challenging start to their 2025 season, losing their first four games. Their most recent outing against the Buffalo Bills ended in a 31-19 loss, marking their fourth consecutive defeat. Despite the loss, the Saints managed to outgain the Bills in first downs with a total of 22 compared to the Bills’ 20.

The Saints’ offensive struggles are evident, especially in the passing game, where they accumulated only 109 yards against the Bills. Spencer Rattler, the team’s quarterback, has had a rough start, with his performance being inconsistent. However, the team has shown some promise in the rushing department, achieving 189 rushing yards in the last game.

Offensive Challenges

Throughout the season, the Saints’ offensive unit ranks 23rd in scoring, with 338 points. Their passing game is also ranked 23rd with 3,488 yards, highlighting a key area that needs improvement. The team’s rushing game has been somewhat more effective, placing 14th with 1,954 yards.

Alvin Kamara continues to be a crucial player for the Saints, leading the team with 256 rushing yards over four games. He has also contributed in the passing game with 13 receptions, adding versatility to the Saints’ offensive strategy.

Defensive Standings

Defensively, the Saints have allowed 398 points, ranking them 18th in opponent scoring. Their pass rush has been effective, with 39 sacks placing them 10th in the league. The defense’s ability to create turnovers is also notable, as they have 14 interceptions, ranking them 6th overall.

Carl Granderson has been a standout on defense, contributing with 5 solo tackles and a sack in the recent game against the Bills. The Saints’ defense needs to maintain their pressure to assist their offense in gaining favorable field positions.

Injury Concerns

Injuries have impacted the Saints, with several key players sidelined. Taysom Hill and Foster Moreau are currently questionable, while players like Will Clapp and Julian Blackmon are out for the season. These absences have affected the team’s depth and on-field performance.

With critical players on the injured reserve list, the Saints will need their depth players to step up and fill the void. The upcoming games will test the team’s resilience and ability to adapt to these challenges.

Upcoming Schedule

The Saints are set to play their next game at home against the New York Giants. This matchup provides an opportunity for the team to secure their first win of the season. Following the Giants, the Saints face the New England Patriots, Chicago Bears, Tampa Bay Buccaneers, and Los Angeles Rams.

Playing at Caesars Superdome should give the Saints an advantage, but they need to capitalize on their home field to turn their season around. The next few games are crucial for the Saints to regain momentum and improve their record.

Team Betting Trends

  • O/U – All Games (REG): Last 3 REG Games (2025) → 3-0 (100.0%)
  • O/U – As Underdog (REG): Last 3 REG Games (2025) → 3-0 (100.0%)
  • O/U – Away Games (REG): Last 3 REG Games (2024–2025) → 3-0 (100.0%)
  • O/U – After Loss (REG): Last 3 REG Games (2025) → 3-0 (100.0%)
  • O/U – Totals ≤ 42 (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)

New York Giants: Navigating the Challenges Ahead

Quarterback Overview

Russell Wilson leads the New York Giants’ offense with 786 passing yards over four games. Despite ranking 20th in the league for passing yards, Wilson has shown resilience with a top team rank in passing touchdowns. His ability to minimize interceptions has been notable, tying for the second-best rank on the team with just three.

Jaxson Dart has played three games and contributed 111 passing yards. Although his numbers are modest, he has managed to throw one touchdown without any interceptions. His performance places him second in team ranks for both categories.

Running Back Insights

Cam Skattebo has been a key player in the Giants’ ground game, rushing for 181 yards in four games. His rank of 27th in the league highlights his impact on the field. Skattebo’s contribution extends to the passing game with 12 receptions, a team-leading statistic.

Tyrone Tracy Jr. has seen limited action, but he has managed 68 rushing yards across three games. Although Tracy hasn’t scored any touchdowns yet, his receiving skills add depth to the Giants’ offensive options. Devin Singletary rounds out the backfield with 52 rushing yards in four games.

Wide Receiver and Tight End Contributions

Malik Nabers has been a standout for the Giants, recording 271 receiving yards and two touchdowns in four games. His efforts place him 14th in the league for receiving yards, highlighting his importance to the Giants’ aerial attack.

Theo Johnson at the tight end position has caught nine passes for 66 yards. He has also secured a touchdown, demonstrating his value in the red zone. Johnson’s contributions have provided a reliable target for the Giants’ quarterbacks.

Defensive Standouts

Dru Phillips has been pivotal in the Giants’ secondary, recording a key interception. His presence on the field adds a layer of security for the Giants’ defense. Meanwhile, Paulson Adebo’s tackling abilities, with six solo tackles, have helped the Giants counter opposing offenses.

The Giants’ defense has excelled at pressuring quarterbacks, with 45 sacks ranking sixth in the league. This pass rush has been essential in disrupting opponent game plans. Additionally, the defense’s ability to recover fumbles has further strengthened their field position control.

Injury Concerns

The Giants are facing significant injury challenges, with several key players out. Notably, Graham Gano is dealing with a groin injury, impacting the kicking game. The absence of Malik Nabers, due to a torn ACL, is a blow to the receiving corps.

Defensive depth is also affected, with Victor Dimukeje and Chris Board on the injured reserve list. These injuries will test the Giants’ roster depth as they aim to remain competitive in upcoming games.

Upcoming Matchups

The Giants will be playing away against the New Orleans Saints. They face a challenging road game, as they are listed as 2.0-point underdogs. The Giants will need to execute efficiently to overcome this deficit.

Looking ahead, the Giants have several tough matchups on the horizon, including games against the Philadelphia Eagles and San Francisco 49ers. These games will be crucial for the Giants as they strive to improve their standing in the league.

New York Giants Top Betting Trends

  • ATS – All Games (REG): Last 3 REG Games (2025) → 2-1 (66.7%)
  • ATS – As Underdog (REG): Last 3 REG Games (2025) → 2-1 (66.7%)
  • SU – Home Games (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • ATS – Home Games (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • ATS – After Loss (REG): Last 3 REG Games (2025) → 2-1 (66.7%)
  • O/U – As Underdog (REG): Last 13 REG Games (2024–2025) → 6-7 (46.2%)
  • O/U – After Loss (REG): Last 13 REG Games (2024–2025) → 6-7 (46.2%)
  • O/U – All Games (REG): Last 14 REG Games (2024–2025) → 6-8 (42.9%)
  • O/U – Home Games (REG): Last 4 REG Games (2024–2025) → 2-2 (50.0%)
  • O/U – Totals ≤ 42 (REG): Last 4 REG Games (2024) → 2-2 (50.0%)
  • O/U – Away Games (REG): Last 7 REG Games (2024–2025) → 3-4 (42.9%)
  • SU – After Loss (REG): Last 5 REG Games (2024–2025) → 2-3 (40.0%)
  • SU – All Games (REG): Last 6 REG Games (2024–2025) → 2-4 (33.3%)
  • SU – As Underdog (REG): Last 6 REG Games (2024–2025) → 2-4 (33.3%)
  • ATS – Away Games (REG): Last 6 REG Games (2024–2025) → 2-4 (33.3%)
  • ATS – Totals ≤ 42 (REG): Last 6 REG Games (2024) → 2-4 (33.3%)
  • SU – Totals ≤ 42 (REG): Last 3 REG Games (2024) → 1-2 (33.3%)
  • SU – Away Games (REG): Last 3 REG Games (2024–2025) → 0-3 (0.0%)

Saints vs Giants Prediction: Over 41.0

The Saints have struggled this season, with a record of 0-4, but their games have consistently exceeded expectations in terms of total points. The Giants, with a 1-3 record, are also finding it tough but have shown potential to score, especially against lower-ranked defenses like the Saints’. Given the trends, this game could see both teams focusing on their offensive capabilities to break their losing streaks.

Both teams rank in the lower half for defensive statistics from last season. The Giants ranked 20th in opponent score, and the Saints were 18th. This suggests defensive vulnerabilities that could be exploited, increasing the likelihood of the game surpassing the 41-point total set by sportsbooks.

New Orleans’ recent over/under trends reveal that their last three games have hit the over. The Saints have also consistently gone over in games with totals set at 42 or below. The controlled environment of the Caesars Superdome further supports a higher-scoring game, free from weather-related disruptions.

Taking into account both teams’ current form, defensive struggles, and offensive potential, the safer play seems to be the over 41.0 points. The projected final score for this game is Saints 24 – Giants 21, just surpassing the line.

  • Saints vs Giants Prediction: Over 41.0
  • Saints vs Giants Score: Saints 24 – Giants 21
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