NFL Game Prediction

Colts vs Raiders Prediction & Betting Tips for NFL Week 5 on 10/5/2025

Want our best Colts vs Raiders prediction for NFL week 5 on 10/5/25? Get our NFL betting tip as the Las Vegas Raiders travel to the Indianapolis Colts on 10/5/25 at Lucas Oil Stadium, in Indianapolis. Knup Sports has your free pick!

The Indianapolis Colts are set to host the Las Vegas Raiders in a Week 5 showdown of the 2025 NFL season at Lucas Oil Stadium. The game is scheduled for Sunday, October 5, 2025, at 1:00 PM and will be broadcast on FOX. With the Colts’ strong home record so far, they aim to continue their momentum against a struggling Raiders team. The Raiders come into the game with a 1-3 record, having won only one road game against the New England Patriots. Led by head coach Pete Carroll, the Raiders will look to improve under the guidance of offensive coordinator Chip Kelly and defensive coordinator Patrick Graham. The team’s recent performance showed potential in their running game, but turnovers remain a concern. In contrast, the Colts boast a 3-1 record, with an undefeated streak at home. Under the leadership of head coach Shane Steichen, Indianapolis has shown a balanced attack with contributions from key players like Jonathan Taylor and Daniel Jones. The Colts’ defense, coordinated by Lou Anarumo, will be crucial in containing the Raiders’ offense.

Colts vs Raiders At a Glance

  • Game Location: Lucas Oil Stadium in Indianapolis, IN with a retractable roof.
  • Game Time: Sunday, October 5, 2025, at 1:00 PM.
  • Broadcast Information: Watch the game on FOX.
  • Indianapolis Colts Record: They have a 3-1 record this season.
  • Las Vegas Raiders Record: The Raiders stand at 1-3 this season.
  • Betting Odds: Colts favored with a moneyline of -314 and a spread of -7.0.

Indianapolis Colts: Ready for the Raiders Challenge

Offensive Strengths

The Indianapolis Colts’ offense has demonstrated a balanced attack with significant contributions from both the passing and rushing games. Ranked 25th in passing yards with 3361, their aerial game has room for improvement but still poses a threat.

The ground game has been a standout, with 2331 rushing yards placing them 8th in the league, showcasing their capability to dominate on the ground.

Defensive Capabilities

Defensively, the Colts have a mixed bag of performances. They rank 23rd in opponent scoring, conceding 427 points, highlighting areas for improvement in defense.

However, their ability to force turnovers is a strong point, with 16 interceptions ranking 4th and 10 fumble recoveries placing them 5th in the league.

Key Players

Daniel Jones has been a key figure in the Colts’ offense, leading the league with 1078 passing yards. Despite a modest four touchdown passes, his ability to move the chains has been crucial.

Jonathan Taylor leads the rushing attack with 414 yards, making him a primary focus for opposing defenses. His three rushing touchdowns underscore his importance to the team’s offensive strategy.

Recent Game Performances

The Colts showed resilience in their recent games, notably against the Tennessee Titans with a 41-20 victory. Their ability to bounce back from a loss to the Rams demonstrates their competitive spirit.

Despite a narrow 29-28 win over the Denver Broncos, the Colts’ performance highlighted their ability to close out tight games. This bodes well for their confidence moving forward.

Injury Report

The Colts are dealing with several key injuries, including Kenny Moore II and Alec Pierce, both questionable for Week 5. Tyler Goodson’s groin issue also poses a concern for the running back depth.

Long-term injuries to players like Blake Freeland and Justin Walley impact the team’s depth and could influence game strategies in upcoming weeks.

Upcoming Game Analysis

The Colts face the Las Vegas Raiders at home, where they are favored by 7 points. With a total of 48 points, the game is expected to be competitive, with the Colts’ home advantage playing a crucial role.

Given their strong home record and recent form, the Colts are well-positioned to continue their winning streak. However, they will need to manage their injuries effectively to ensure success.

Betting Trends

  • O/U – After Loss (REG): Last 5 REG Games (2024) → 5-0 (100.0%)
  • SU – Home Games (REG): Last 4 REG Games (2024–2025) → 4-0 (100.0%)
  • ATS – Home Games (REG): Last 4 REG Games (2024–2025) → 4-0 (100.0%)
  • SU – After Loss (REG): Last 4 REG Games (2024) → 4-0 (100.0%)
  • SU – As Favorite (REG): Last 3 REG Games (2024–2025) → 3-0 (100.0%)

Las Vegas Raiders: Gearing Up for the Indianapolis Challenge

Offensive Overview

The Las Vegas Raiders’ offense has shown strengths in passing, with a season total of 3,797 yards, ranking 13th in the league. However, their rushing game struggles, sitting at 31st with only 1,357 yards. Their overall score production ranks 27th, a concern when facing teams with strong defensive records.

Defensive Outlook

Defensively, the Raiders have managed to secure a mid-tier ranking, allowing 5,663 opponent offensive yards, placing them 15th. They have been effective at pressuring quarterbacks, with 38 sacks, ranking 11th. The defense has also been opportunistic, ranking 10th in opponent passing interceptions with 10 for the season.

Recent Performances

In their recent home game against the Chicago Bears, the Raiders narrowly lost 25-24, despite outrushing their opponents significantly. The team’s passing game was less effective, with just 117 yards and three interceptions by Geno Smith. Their road game against Washington saw a 41-24 defeat, even with a solid passing performance of 261 yards.

Against the Los Angeles Chargers, the Raiders struggled offensively in a 20-9 loss, managing only 150 passing yards. They did secure their only win of the season against the New England Patriots, a 20-13 victory, with Geno Smith throwing for 333 yards. This win highlighted their potential when executing effectively.

Key Players

Geno Smith, the Raiders’ quarterback, is ranked 8th in the league with 948 passing yards and first on the team. However, his seven interceptions are a concern, ranking 35th. Running back Ashton Jeanty leads the rushing game with 282 yards and two touchdowns, while Tre Tucker stands out in the receiving corps with four touchdowns and 224 receiving yards.

Injury Concerns

The Raiders’ offensive line will miss Kolton Miller, who is out with an ankle injury. Additionally, safety Lonnie Johnson Jr. is sidelined with a fibula injury. Both players are on injured reserve and will miss at least four games, impacting the team’s depth.

Betting Trends

  • O/U – As Underdog (REG): Last 11 REG Games (2024–2025) → 6-5 (54.5%)
  • O/U – After Loss (REG): Last 11 REG Games (2024–2025) → 6-5 (54.5%)
  • O/U – All Games (REG): Last 3 REG Games (2025) → 2-1 (66.7%)
  • SU – As Favorite (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • ATS – As Favorite (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • O/U – Home Games (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • SU – Away Games (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • ATS – Away Games (REG): Last 3 REG Games (2024–2025) → 2-1 (66.7%)
  • SU – Totals ≤ 42 (REG): Last 3 REG Games (2024) → 2-1 (66.7%)
  • ATS – Totals ≤ 42 (REG): Last 3 REG Games (2024) → 2-1 (66.7%)

Colts vs Raiders Prediction: Colts -7.0

The Indianapolis Colts enter this game with a strong 3-1 record, and they have been particularly impressive at home with a 2-0 record. Their recent performances at Lucas Oil Stadium suggest they have a significant edge over the 1-3 Las Vegas Raiders. The Colts are favored by 7.0 points, and with their current form, they are likely to cover this spread.

Looking at the Raiders, their road performance this season stands at 1-1, and they have struggled against a Colts team that has defeated them in their last few encounters. With a head-to-head history favoring Indianapolis, the Raiders may find it challenging to keep up. Additionally, the Raiders’ offense ranks 27th in scoring, which could be problematic against the Colts’ home advantage.

On the defensive side, the Colts have been solid, allowing fewer points compared to the Raiders. The Colts also have an impressive streak of covering the spread as favorites, which strengthens their case for this game. Given these factors, betting on the Colts to cover the -7.0 spread is the recommended choice.

Given the Colts’ current momentum and home-field advantage, they should be able to secure a comfortable win. A projected final score of Indianapolis Colts 30 – Las Vegas Raiders 17 supports the decision to back the Colts at -7.0.

  • Colts vs Raiders Prediction: Colts -7.0
  • Colts vs Raiders Score: Colts 30 – Raiders 17
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