MLB Game Prediction

New York Yankees vs Baltimore Orioles Prediction & Betting Tips for 9/28/2025

Want our best New York Yankees vs Baltimore Orioles prediction for 9/28/25? Get our MLB betting tip as the Orioles travel to the Yankees on 9/28/25 at Yankee Stadium, in New York. Knup Sports has your free pick!

The Baltimore Orioles will travel to Yankee Stadium to take on the New York Yankees in a Sunday afternoon game on September 28, 2025. The Orioles, currently ranked fifth in the AL East with a record of 75-86, are looking to break their two-game losing streak. Interim manager Tony Mansolino will be leading the team as they hope to improve their recent form of 4-6 in the last ten games.

In contrast, the New York Yankees are riding high, holding the top spot in the AL East with a record of 93-68. Under the guidance of manager Aaron Boone, the Yankees have been on an impressive seven-game winning streak. Their recent form is particularly strong at 9-1 over the last ten games, and they boast a solid home record of 49-31.

The game will be played at Yankee Stadium under clear skies with a mild breeze, making for ideal conditions for baseball. Fans can catch the action on MASN, as the Yankees aim to continue their winning momentum against a struggling Orioles squad. With both teams’ recent performances, the Yankees are favored with a moneyline of -191 compared to the Orioles’ +157.

Yankees vs Orioles At a Glance

  • Teams Competing: Baltimore Orioles vs New York Yankees
  • Records and Standings: Orioles at 75-86, 5th in AL East; Yankees at 93-68, 1st in AL East
  • Game Venue: Yankee Stadium, New York, NY
  • Game Timing: Sunday, September 28, 2025 at 3:05 PM
  • Weather Conditions: Clear skies with a mild breeze
  • Broadcast Information: Available on MASN

New York Yankees Ready to Make Their Mark Against the Orioles

Orioles Lineup Overview

The Baltimore Orioles come into the game with a balanced lineup, featuring a mix of power and contact hitters. Their ability to adapt to different pitching styles makes them a team to watch. The Orioles’ strategy often revolves around getting runners on base and capitalizing on scoring opportunities.

Kyle Bradish is slated to take the mound for the Orioles, bringing with him an impressive ERA of 2.25. His ability to keep the ball in the park and limit base runners has been crucial for Baltimore. Bradish’s command will be key as he faces a potent Yankees lineup.

Key Orioles Players to Watch

Adley Rutschman, the Orioles’ catcher, is a young player to keep an eye on with his defensive prowess and potential at the plate. His presence behind the dish can influence the Yankees’ running game. Rutschman’s ability to handle pitchers is also noteworthy.

Ryan Mountcastle adds power to the Orioles’ lineup and can change the game with a single swing. His role in the middle of the order makes him a constant threat to opposing pitchers. Keeping him in check will be vital for the Yankees’ pitching staff.

Orioles’ Offensive Strategy

The Orioles rely on a combination of speed and power to generate runs, often looking to steal bases and take extra bases on hits. Their aggressive baserunning can pressure opposing defenses into making mistakes. This approach, however, could also lead to outs on the bases if not executed well.

Patience at the plate is another aspect of Baltimore’s offensive game plan, as they aim to drive up pitch counts and get into the bullpen early. They lead the league in walks, which highlights their selective approach. This patience can be a double-edged sword if they fall behind in counts too often.

Team Betting Trends

  • Orioles as Favorite: 52-39 (57.1%)
  • Orioles as Underdog: 38-51 (42.7%)
  • Orioles in Night Games: 60-54 (52.6%)
  • Orioles in Day Games: 30-36 (45.5%)
  • Orioles in Home Games: 48-33 (59.3%)
  • Orioles in Away Games: 42-57 (42.4%)
  • Orioles vs Division Opponents: 35-37 (48.6%)
  • Orioles vs League Opponents: 55-53 (50.9%)

Orioles Prepare for Season Finale at Yankee Stadium

Team Overview

The Baltimore Orioles approach the end of a challenging season, finishing with a 75-86 record. Despite a strong start, their performance dwindled, eliminating them from postseason contention. The Orioles now face the Yankees, aiming to close the season on a positive note.

This season’s offensive struggles are evident in their .235 batting average, ranking 16th in the league. Their on-base percentage is .305, placing them 18th, highlighting the need for improved plate discipline.

Key Players

Gunnar Henderson has been a standout for the Orioles, leading the team with a .274 average and 16 home runs. His consistency at shortstop has been a bright spot in an otherwise difficult season.

Jackson Holliday, the Orioles’ second baseman, has shown potential with 17 home runs and a .242 batting average. His performance provides hope for a stronger offensive output next season.

Pitching Challenges

The Orioles’ pitching staff has faced difficulties, with a team ERA of 4.62, ranking 26th in the league. Home runs have been a particular issue, with 215 allowed, placing them 24th.

Starting pitcher Kyle Bradish will take the mound against the Yankees, boasting a solid 2.25 ERA. His performance will be crucial in containing a potent Yankees lineup.

Betting Trends

  • SU Last 3 Games: 1-2 (33.3%)
  • SU as Underdog: 43-51 (45.7%)
  • Runline All Games: 77-84 (47.8%)
  • O/U All Games: 66-95 (41.0%)

Yankees vs Orioles Prediction: Under 8.5

The New York Yankees enter this final game of the regular season in stellar form, having won their last seven games. Their ability to limit opponents has been notable, especially with their pitching performance, including a recent 6-1 victory against the Orioles. The team’s strong defense and pitching are likely to control the game’s pace, keeping the score low. On the other hand, the Baltimore Orioles have struggled offensively, finishing the season with a disappointing record and only managing two hits in their last encounter with Yankees pitcher Cam Schlittler. With Orioles’ starter Kyle Bradish holding a 2.25 ERA, the potential for a low-scoring game is high. The Yankees’ Luis Gil, with a 3.29 ERA, adds to the outlook of a pitching-dominated game. The Yankees’ recent games have leaned towards the under, with their last ten games hitting the under 70% of the time. Additionally, their games at home have seen the under 45% of the time this season, further suggesting a game that may fall below the set total. Given these trends, the under 8.5 seems to be a solid choice. In conclusion, the combination of strong pitching from both teams and recent trends supports the under 8.5 total. A projected final score of Yankees 4 – Orioles 2 aligns with this prediction.

  • Yankees vs Orioles Prediction: Under 8.5
  • Yankees vs Orioles Score: Yankees 4 – Orioles 2
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