Buccaneers vs Eagles Prediction & Betting Tips for NFL Week 4 on 9/28/2025

The Philadelphia Eagles travel to Raymond James Stadium to face the Tampa Bay Buccaneers in a highly anticipated Week 4 game of the 2025 NFL season. Both teams come into this contest with perfect 3-0 records, making this a critical showdown for momentum in the early part of the season. The game is set for Sunday, September 28, 2025, at 1:00 PM and will be broadcast on FOX. Under the leadership of head coach Nick Sirianni, the Eagles have demonstrated impressive performances this season, including a recent victory over the Los Angeles Rams with a score of 33-26. Key players such as Jalen Hurts and A.J. Brown have been instrumental in their success, contributing significantly in each of their wins. The Eagles will aim to maintain their unbeaten streak as they face a strong Buccaneers team. The Tampa Bay Buccaneers, coached by Todd Bowles, also boast a 3-0 record, highlighted by a narrow 29-27 win against the New York Jets in their last outing. Quarterback Baker Mayfield has shown solid form, supported by a robust receiving corps including Mike Evans and Emeka Egbuka. The Buccaneers will look to defend their home turf at Raymond James Stadium against a formidable Eagles squad.

Buccaneers vs Eagles At a Glance

• Game Date & Time: Sunday, September 28, 2025, at 1:00 PM.
• Stadium: Raymond James Stadium in Tampa Bay, FL.
• Weather: Specific weather conditions are not available.
• TV Channel: The game will be broadcast on FOX.
• Philadelphia Eagles Record: 3-0-0 this season.
• Tampa Bay Buccaneers Record: 3-0-0 this season.

Buccaneers Seek to Maintain Momentum in Crucial Matchup

Quarterback Performance

The Tampa Bay Buccaneers have enjoyed a strong start to the season, in large part due to the consistent play of quarterback Baker Mayfield. In three games, Mayfield has amassed 615 passing yards, ranking him 18th in the league. He has thrown six touchdowns without an interception, showcasing efficient decision-making.

Mayfield’s ability to avoid turnovers has been crucial, as it allows the Buccaneers to sustain drives and maintain control in games. His league-leading efficiency has put Tampa Bay’s passing game in a favorable position moving forward.

Offensive Weapons

Running back Bucky Irving has been a key component in the Buccaneers’ offensive scheme, contributing both on the ground and through the air. Irving has tallied 174 rushing yards and 91 receiving yards, proving to be a versatile asset for Tampa Bay.

Wide receiver Emeka Egbuka has also been pivotal, leading the team with 181 receiving yards and three touchdowns. His ability to find the end zone and create big plays has added another dimension to the Buccaneers’ offense.

Defensive Outlook

The Buccaneers’ defense has shown resilience, allowing 385 points over the season and ranking 15th in opponent scoring. With 46 sacks, they rank 5th in this category, highlighting their ability to pressure opposing quarterbacks.

Additionally, the defense has recovered 12 fumbles, ranking 4th, which has been instrumental in flipping the field and providing the offense with advantageous positions.

Injury Concerns

Tampa Bay is dealing with several injuries, which may impact their game plan. Notably, wide receiver Mike Evans is ruled out with a hamstring injury, which could affect the passing attack.

Several other key players, including Chris Godwin and Tristan Wirfs, are listed as questionable, adding uncertainty to the team’s readiness for the upcoming game.

Team Betting Trends

• ATS – Away Games (REG): Last 6 REG Games (2024–2025) → 6-0 (100.0%)
• SU – All Games (REG): Last 10 REG Games (2024–2025) → 9-1 (90.0%)
• ATS – All Games (REG): Last 10 REG Games (2024–2025) → 9-1 (90.0%)
• SU – As Favorite (REG): Last 9 REG Games (2024–2025) → 8-1 (88.9%)
• ATS – As Favorite (REG): Last 9 REG Games (2024–2025) → 8-1 (88.9%)
• SU – Home Games (REG): Last 4 REG Games (2024–2025) → 4-0 (100.0%)
• SU – After Win (REG): Last 4 REG Games (2024–2025) → 4-0 (100.0%)
• ATS – After Win (REG): Last 8 REG Games (2024–2025) → 7-1 (87.5%)
• O/U – Home Games (REG): Last 3 REG Games (2024–2025) → 3-0 (100.0%)

The Philadelphia Eagles Take Flight in Tampa Bay

Team Overview

The Philadelphia Eagles are entering this game with a strong offensive and defensive performance this season. Ranking 7th in total score, their offense has shown efficiency despite a lower 29th rank in passing yards. The Eagles have demonstrated dominance in rushing yards, securing the 2nd position with 3048 yards.

Defensively, the Eagles have been exceptional, holding opponents to 303 points, which ranks them 2nd. They lead the league in opponent offensive yards, allowing only 4732 yards. Their aggressive defense also has accumulated 41 sacks, placing them in the 8th position.

Recent Performance

The Eagles have started the 2025 regular season on a high note with a 3-0 record. Their recent victory over the Los Angeles Rams at home with a score of 33-26 showcased their resilience. Key offensive players like Jalen Hurts, who threw for 226 yards and 3 touchdowns, and A.J. Brown, with 109 receiving yards and a touchdown, were instrumental in their success.

In their previous outing against the Kansas City Chiefs, the Eagles secured a narrow 20-17 win. Despite a challenging game with only 94 passing yards, their rushing game with Saquon Barkley at the helm proved crucial. Barkley recorded 88 rushing yards and a touchdown, contributing significantly to the win.

Key Players to Watch

Jalen Hurts continues to be a vital part of the Eagles’ offensive strategy. With 479 passing yards and 3 touchdowns in the season, Hurts ranks 28th in the league for passing yards. Saquon Barkley remains a key player in the backfield, with 194 rushing yards and two touchdowns, making him a threat on the ground.

A.J. Brown and DeVonta Smith are crucial targets in the receiving corps, combining for 27 receptions and 273 receiving yards. Dallas Goedert has also been a reliable option, especially in tight situations, with 77 receiving yards and a touchdown.

Team Betting Trends

• SU – All Games (REG): 14-1 (93.3%)
• ATS – All Games (REG): 14-1 (93.3%)
• SU – Home Games (REG): 8-0 (100.0%)
• SU – As Favorite (REG): 12-1 (92.3%)
• ATS – As Favorite (REG): 12-1 (92.3%)
• SU – After Win (REG): 12-1 (92.3%)
• ATS – After Win (REG): 12-1 (92.3%)
• ATS – Away Games (REG): 7-0 (100.0%)

Buccaneers vs Eagles Prediction: Over 43.5

The Philadelphia Eagles and Tampa Bay Buccaneers both enter this game with a perfect 3-0 record, suggesting strong offensive capabilities. The Eagles have shown a solid performance with their 7th ranked scoring offense last season, while the Buccaneers ranked 4th. This offensive prowess hints at a high-scoring game.

The Buccaneers’ offense, ranked 4th in scoring and 3rd in passing yards last season, has been prolific. Additionally, their past games against the Eagles have seen scores go over the total of 43.5 multiple times, indicating a trend that could continue. Both teams have explosive offenses that can capitalize on any defensive lapses.

Defensively, while the Eagles have been strong, ranking 2nd in opponent scoring, the Buccaneers’ offense has consistently found ways to score against top defenses. With the Buccaneers having a 66.7% over rate in their last 15 games, the potential for a high-scoring game is present.

Considering both teams’ offensive strengths and historical scoring patterns, the prediction leans towards the game going over the set total of 43.5 points. A projected score of Eagles 27, Buccaneers 21 supports this outlook.

• Buccaneers vs Eagles Prediction: Over 43.5
• Buccaneers vs Eagles Score: Eagles 27 – Buccaneers 21