The Indianapolis Colts are set to host the Denver Broncos at Lucas Oil Stadium in Week 2 of the 2025 NFL season. Both teams enter the game with a 1-0 record, looking to build on their strong starts. The game will air on CBS at 4:05 PM on Sunday, September 14, 2025.
Denver, under the guidance of head coach Sean Payton, recently secured a win against the Tennessee Titans with a score of 20-12. The Broncos showed a balanced offensive attack, combining 166 passing yards and 151 rushing yards in their opening game. Their defense was also effective, limiting the Titans to just 62 passing yards.
The Colts, led by head coach Shane Steichen, opened their season with a commanding 33-8 victory over the Miami Dolphins. Quarterback Daniel Jones was instrumental in the win, passing for 272 yards. The Colts’ defense was equally impressive, holding Miami to only 133 passing yards and intercepting two passes.
Colts vs Broncos At a Glance
- Game Date: Sunday, September 14, 2025, at 4:05 PM
- Stadium: Lucas Oil Stadium, Indianapolis, IN — Retractable Roof
- TV Channel: CBS
- Denver Broncos Record: 1-0-0
- Indianapolis Colts Record: 1-0-0
- Game Odds: Broncos favored with a moneyline of -127
The Indianapolis Colts: A Closer Look at Their Game Performance
Offensive Overview
The Indianapolis Colts concluded the last regular season with a total score of 377, ranking 16th in the league. Their passing game accumulated 3,361 yards, positioning them at 25th place, while their rushing attack was more effective, amassing 2,331 yards to secure the 8th rank.
First downs have been a moderate point of strength for the Colts, securing 315 and placing them 19th in the league. On third down conversions, they have a 37.9% success rate, ranked 16th overall.
Defensive Analysis
Defensively, the Colts have struggled, allowing 427 points, which places them 23rd. Despite this, they have maintained a respectable sack count with 36, securing the 13th rank.
The Colts have shown a knack for creating turnovers with 16 interceptions and 10 fumbles recovered, ranking 4th and 5th respectively. However, they have conceded a substantial 6,140 opponent yards, ranking near the bottom at 29th.
Key Players in Recent Game
In their recent victory over the Miami Dolphins, Daniel Jones led the charge with 272 passing yards and a touchdown. Michael Pittman Jr. stood out among the receivers with 80 yards and a touchdown, while Jonathan Taylor added 71 rushing yards.
Defensively, Kenny Moore II, Nick Cross, and Samson Ebukam each recorded a sack, contributing to a dominant 33-8 win. The team’s ability to force turnovers was on display with two interceptions.
Injury Concerns
The Colts face several injury challenges, with D.J. Montgomery, Salvon Ahmed, and Jacob Phillips among those on injured reserve. Tyler Goodson and Jaylon Jones are listed as questionable for Week 2.
These injuries could impact the team’s depth and performance in upcoming games, particularly in key positions like wide receiver and running back.
Upcoming Games
Looking ahead, the Colts are set to face the Denver Broncos at home, followed by two away games against the Tennessee Titans and Los Angeles Rams. These matchups will test the Colts’ ability to maintain their early success.
The Colts will also host the Las Vegas Raiders and Arizona Cardinals, providing further opportunities to capitalize on their home-field advantage at Lucas Oil Stadium.
Betting Trends
- SU Last 3: 1-0 (100.0%)
- SU Last 5: 1-0 (100.0%)
- SU Last 10: 1-0 (100.0%)
- SU All Games: 1-0 (100.0%)
- SU as Favorite: 1-0 (100.0%)
- SU in Day Games: 1-0 (100.0%)
- SU in Home Games: 1-0 (100.0%)
- ATS Last 3: 1-0 (100.0%)
- ATS Last 5: 1-0 (100.0%)
- ATS Last 10: 1-0 (100.0%)
- ATS All Games: 1-0 (100.0%)
- ATS as Favorite: 1-0 (100.0%)
- ATS in Home Games: 1-0 (100.0%)
- O/U Last 3: 0-1 (0.0%)
- O/U Last 5: 0-1 (0.0%)
- O/U Last 10: 0-1 (0.0%)
- O/U All Games: 0-1 (0.0%)
- O/U as Favorite: 0-1 (0.0%)
- O/U in Home Games: 0-1 (0.0%)
Denver Broncos Ready to Ride into Week 2: A Look at Their Season Opener and Upcoming Challenge
Team Offense Overview
The Denver Broncos’ offensive unit closed the 2024 season ranked 10th in scoring, tallying 425 points. Their passing game amassed 3,610 yards, placing them 20th in the league, while their rushing attack produced 1,908 yards, earning them a 16th-place ranking. They also secured 315 first downs, ranking 19th overall.
On third downs, the Broncos converted 39.6% of their attempts, which was good for 13th in the NFL. This efficiency is crucial for sustaining drives and keeping their defense fresh. As they face the Colts, maintaining or improving their conversion rate will be key.
Defensive Prowess
The Broncos’ defense is coming off an impressive 2024 campaign, where they ranked 3rd in opponent scoring, allowing just 311 points. Their pass rush led the league with 63 sacks, and they managed to snag 15 interceptions, ranking 5th. Additionally, the unit recovered 9 fumbles, placing them 6th in that category.
Overall, they allowed 5,391 opponent offensive yards, which was the 7th best in the NFL. Their defensive strength will be tested against the Colts, and their ability to pressure the quarterback and create turnovers will be vital.
Recent Performance
In Week 1 of the 2025 season, the Broncos secured a 20-12 victory over the Tennessee Titans at home. Their defense was stifling, allowing just 7 first downs and 62 passing yards. The Broncos’ offensive charge was led by J.K. Dobbins and Courtland Sutton, both of whom found the end zone.
Quarterback Bo Nix had a mixed outing, throwing for 176 yards with 1 touchdown but also 2 interceptions. As the team prepares for Week 2, reducing turnovers will be crucial for continued success.
Key Players and Injuries
Key contributors in their opening game included J.K. Dobbins, who rushed for 63 yards and a touchdown, and Courtland Sutton, who had 61 receiving yards and a touchdown. The defense was led by Talanoa Hufanga, who recorded 7 solo tackles.
The Broncos face some injury concerns heading into Week 2, with Evan Engram, Dre Greenlaw, and Nate Adkins listed as questionable. Michael Burton and Malcolm Roach are among those on injured reserve, impacting depth in key positions.
Upcoming Challenge
The Broncos will face the Indianapolis Colts on September 14, 2025, at Lucas Oil Stadium. It will be their first away game of the season, and they will look to build on their solid Week 1 performance.
With their strong defensive statistics from last season, the Broncos will aim to contain the Colts’ offensive threats. The focus will be on maintaining their defensive standards while seeking to improve their offensive efficiency.
Team Betting Trends
- SU Last 3: 1-0 (100.0%)
- ATS Last 3: 0-1 (0.0%)
- O/U Last 3: 0-1 (0.0%)
- SU as Favorite: 1-0 (100.0%)
- ATS as Favorite: 0-1 (0.0%)
- O/U as Favorite: 0-1 (0.0%)
Colts vs Broncos Prediction: Over 42.5
The Denver Broncos showed a strong offensive performance last season, ranking 10th in scoring with 425 points. With Sean Payton at the helm and Joe Lombardi as offensive coordinator, the Broncos are expected to maintain a high-scoring approach. Additionally, their defense, while strong in limiting opponent scores, faces an Indianapolis team that has improved offensively.
The Colts, under Shane Steichen, have demonstrated a balanced offensive attack, ranking 8th in rushing yards last season. With the retractable roof at Lucas Oil Stadium, weather conditions will not hinder either team’s offensive capabilities. This sets the stage for both teams to potentially exceed their average scoring marks from last season.
Recent head-to-head games between the Broncos and Colts have often gone over the posted totals. For instance, their last preseason game saw a combined score of 64 points. Given these trends and offensive capabilities, the total of 42.5 points seems achievable.
Considering both teams’ offensive and defensive stats, along with recent head-to-head results, a projected score of Broncos 28 – Colts 24 supports picking the over. Both teams are likely to exploit each other’s defensive vulnerabilities, leading to a high-scoring game.
- Colts vs Broncos Prediction: Over 42.5
- Colts vs Broncos Score: Broncos 28 – Colts 24
