MLB Game Prediction

Pittsburgh Pirates vs Milwaukee Brewers Prediction & Betting Tips for 9/6/2025

Want our best Pittsburgh Pirates vs Milwaukee Brewers prediction for 9/6/25? Get our MLB betting tip as the Brewers travel to the Pirates on 9/6/25 at PNC Park, in Pittsburgh. Knup Sports has your free pick!

The Milwaukee Brewers will take on the Pittsburgh Pirates at PNC Park in Pittsburgh, PA, on Saturday, September 6, 2025, at 6:40 PM. With a strong record of 87-55, the Brewers are currently leading the NL Central. On the other hand, the Pirates, with a record of 64-78, are positioned at the bottom of the same division.

The Brewers are coming off a 5-2 win against the Pirates, showcasing their capabilities as a top team in the division. Managed by Pat Murphy, they have demonstrated consistency with a 41-29 road record. The Pirates, under the management of Don Kelly, have shown improvement, winning 7 out of their last 10 games, despite their recent loss.

Weather forecasts for the game predict overcast clouds with mild temperatures and a light breeze, making for an intriguing outdoor game atmosphere. Fans can catch the game on the FDSWI channel, with both teams eager to gain momentum as the season progresses. The Brewers are slightly favored with a moneyline of -155 against the Pirates’ +132.

Pirates vs Brewers At a Glance

  • Game Location: PNC Park in Pittsburgh, PA, a renowned outdoor field.
  • Brewers Record: Leading the NL Central with an 87-55 record.
  • Pirates Recent Form: They have won 7 of their last 10 games.
  • Weather Forecast: Mild day with light breeze and overcast clouds expected.
  • Game Odds: Brewers moneyline set at -155, while the Pirates are at +132.
  • TV Broadcast: Catch the game on FDSWI.

Pirates Look to Turn the Tide Against Brewers

Hitting Overview

The Pirates’ lineup has been struggling to make a significant impact this season, with a batting average of .234, ranking 18th in the league. While they have managed to get on base with a .307 on-base percentage, their slugging percentage of .352 ranks a disappointing 25th. This lack of power is further evidenced by their low home run total of 102, placing them 27th in the league.

Despite these challenges, the Pirates have shown some discipline at the plate with 464 walks, ranking 9th. Their base running has been more promising, with 105 stolen bases placing them 11th. However, the team needs to cut down on strikeouts, with 1235 this season, placing them 22nd.

Pitching Insights

Pittsburgh’s pitching staff has been a bright spot, maintaining an earned run average (ERA) of 3.87, which ranks 8th in the league. They have effectively limited opponents to a .236 batting average against, ranking 7th. Despite giving up 135 home runs, which ranks 3rd, the staff has delivered 51 quality starts, ranking 11th.

The bullpen has been solid, with only 22 blown saves, placing them 8th. Strikeouts remain a concern, with 1124 strikeouts putting them at 21st in the league. However, the overall performance has kept the team competitive in many games.

Key Players to Watch

Andrew McCutchen continues to be a leader for the Pirates, playing in 121 games with a .243 batting average and contributing 13 home runs. Spencer Horwitz, with a .260 average and 7 home runs, has been a consistent presence at first base. Nick Gonzales stands out with a .279 batting average, providing stability in the middle infield.

Jared Triolo, despite some defensive struggles, has been reliable at shortstop, while Joey Bart has shown potential behind the plate with a .247 average. Henry Davis, despite a low average, provides occasional power with 6 home runs.

Starting Pitcher Breakdown

Mitch Keller takes the mound for the Pirates with a 6-13 record and a 4.21 ERA. His performance will be crucial against the Brewers’ Brandon Woodruff, who has a 3.69 ERA and a 5-2 record. Keller’s ability to limit walks and keep hitters off balance will be key to giving the Pirates a chance.

Keller’s experience will be important as the Pirates aim to contain Milwaukee’s offense. With a WHIP of 1.28, Keller will look to minimize baserunners and deliver a strong outing to support his team.

Betting Trends

  • SU Last 3 Games: 2-1 (66.7%)
  • SU in Home Games: 42-31 (57.5%)
  • Runline in Home Games: 45-28 (61.6%)
  • O/U All Games: 58-84 (40.8%)

Brewers Look to Capitalize on Recent Momentum Against Pirates

Team Overview and Performance

The Milwaukee Brewers have been showcasing strong performance this season, standing 87-55 and positioning themselves well in the NL Central title race. Their recent victory against the Pittsburgh Pirates adds momentum, as they head into another away game at PNC Park. With a solid lineup and depth in their roster, the Brewers aim to maintain their winning form.

The Brewers’ offense ranks second in both batting average (.259) and on-base percentage (.331), indicating a potent lineup. Their ability to get on base consistently allows them to create scoring opportunities, even if their slugging percentage (.407) ranks 11th. Their lineup includes players like Brice Turang and William Contreras, who have been pivotal this season.

Key Player Performances

Brice Turang has been a standout player for the Brewers, with a .292 batting average, 17 home runs, and 71 RBIs. His consistent performance at second base makes him a key player to watch. Meanwhile, William Contreras has matched Turang’s home run tally with 17 and maintains a .263 batting average, providing significant offensive support.

Jackson Chourio and Christian Yelich also play crucial roles, contributing to the team’s power with 18 and 27 home runs, respectively. Yelich’s ability to drive in runs, as evidenced by his 92 RBIs, adds another layer of threat to the Brewers’ lineup. These players form the backbone of an offense that can change the course of a game.

Pitching Staff and Recent Adjustments

Brandon Woodruff takes the mound for the Brewers, carrying a 3.69 ERA and a 5-2 record. His WHIP of 1.02 indicates his ability to limit baserunners effectively. Woodruff’s performance will be critical against the Pirates, as they look to secure another win.

The Brewers’ pitching staff is adjusting to recent injuries, with Carlos Rodriguez being called up from Triple-A Nashville. These changes are in response to bullpen injuries, including Nick Mears’ back tightness, impacting their roster. Despite these challenges, the Brewers’ pitching depth continues to perform, with a team ERA of 3.62, ranking second in the league.

Team Betting Trends

  • SU Last 3 Games: 2-1 (66.7%)
  • Runline as Underdog: 44-19 (69.8%)
  • O/U in Away Games: 34-36 (48.6%)
  • Runline when Scoring 5+: 61-11 (84.7%)
  • SU After a Win: 55-32 (63.2%)

Injury Impact

The Brewers have been managing several injuries, with notable players like Shelby Miller and Rhys Hoskins on the injured list. Miller’s absence due to a UCL sprain affects their bullpen, while Hoskins’ thumb sprain impacts the depth of their lineup. Despite these setbacks, the team has demonstrated resilience and depth.

Christian Yelich’s day-to-day status with back soreness is another factor to monitor. His performance can significantly influence the Brewers’ success. The Brewers will need to carefully manage these injury concerns as they continue their pursuit of postseason success.

Pirates vs Brewers Prediction: Brewers -155

The Milwaukee Brewers hold the upper hand in this contest with their impressive 87-55 record and first place in the NL Central. Despite the Pirates’ recent 7-3 run in their last ten games, Milwaukee’s consistent performance against Pittsburgh this season, winning seven of the last ten encounters, gives them the edge. Brandon Woodruff, with a solid ERA of 3.69, adds a layer of security for the Brewers on the mound.

On the other side, the Pittsburgh Pirates, sitting in fifth place in the division, have a noteworthy home record but struggle against division opponents with a 22-40 record. Mitch Keller’s 4.21 ERA doesn’t provide the same level of reliability as his counterpart Woodruff. The Pirates’ bats have been inconsistent, ranking low in several offensive categories, which could be problematic against Milwaukee’s strong pitching staff.

Milwaukee’s hitting has been a driving force, with a second-ranked batting average and on-base percentage. While their slugging percentage is not as high, they have the necessary offensive depth to capitalize on Pittsburgh’s pitching shortcomings. The Brewers’ ability to perform in high-pressure situations, evidenced by their recent victories over the Pirates, underscores their advantage.

The Brewers’ ability to outscore the Pirates by an average margin in head-to-head games this season reflects their overall superiority. Expect Milwaukee to maintain their winning ways with a projected final score of Brewers 5 – Pirates 3, further solidifying their position atop the division standings.

  • Pirates vs Brewers Prediction: Brewers -155
  • Pirates vs Brewers Score: Brewers 5 – Pirates 3
To Top