Louisville Cardinals vs Notre Dame Fighting Irish Matchup

Check out our free Louisville Cardinals vs Notre Dame Fighting Irish pick and preview for this CFB week 5 game in Notre Dame. See who we like to win and cover the spread in this week 5 CFB matchup.

PEAC will be handling the TV broadcast as the Notre Dame Fighting Irish host the Louisville Cardinals at Notre Dame Stadium. Kick-off is set for 3:30 ET. Notre Dame comes in with a 3-1 record, and they are currently favored at -6.5 points in the point spread. The over/under line is at 47.5 points. Louisville is 3-0 so far this season.

Cardinals vs. Fighting Irish Matchup At A Glance

Sport: CFB
Teams: Louisville Cardinals at Notre Dame Fighting Irish
Where: Notre Dame at Notre Dame Stadium
Date: Saturday, September 28th
Betting Odds ND -6.5, LOU +190 | ND -231 O/U 47.5

Cardinals Preview:

Remaining undefeated, Louisville sits at 3-0 after a 31-19 win over Georgia Tech. The Cardinals, who were -9.5 point favorites, covered the spread and took the over/under to 50 points, which was below the line of 56.5 points.

After a 7-7 tie in the first quarter, Louisville took a 17-14 lead at the half. The Cardinals extended their lead in the third quarter, and despite Georgia Tech narrowing the gap in the fourth, Louisville came out on top.

Cardinals Offense Breakdown

In their 31-19 win over Georgia Tech, Louisville's offense totaled 332 yards, with 269 yards coming through the air. Tyler Shough completed 13 of 19 passes (68.4%) for 269 yards, two touchdowns, and a passer rating of 146.27. Ja'Corey Brooks was his top target, catching four passes for 125 yards and a touchdown.

The Cardinals struggled to establish the run, gaining just 63 yards on 24 carries. Donald Chaney led the ground game with 23 yards on 10 attempts.

Cardinals Team Defense

Louisville's defense will be looking to improve after allowing 410 total yards to Georgia Tech in their last game. The Cardinals gave up 312 passing yards on 21 completions, and their secondary will need to tighten up in the next game. Against the run, they were more effective, holding Georgia Tech to just 98 yards on 37 carries. Louisville's defense will be looking to improve after allowing 410 total yards to Georgia Tech in their last game. The Cardinals gave up 312 passing yards on 21 completions, and their secondary will need to tighten up in the next game. Against the run, they were more effective, holding Georgia Tech to just 98 yards on 37 carries.

Fighting Irish Preview:

Fighting Irish Offense Breakdown

Notre Dame's offense was dominant in their 28-3 win, racking up 428 total yards and 24 first downs. The ground game was particularly effective, with the Fighting Irish rushing for 270 yards and three touchdowns. Quarterback Riley Leonard also contributed to the ground attack, rushing for 143 yards and two scores.

Leonard completed 16 of 25 passes for 154 yards, with one touchdown. Beaux Collins was his top target, catching four passes for 60 yards and a score.

Fighting Irish Team Defense

Notre Dame's defense was effective in their most recent game, holding Miami (OH) to just 3 points and 229 total yards. The Irish secondary was particularly strong, limiting Miami's passing attack to just 119 yards on 14 completions. Notre Dame also came away with two interceptions. Against the run, the Irish allowed 110 yards, but they did not concede a rushing touchdown.

Cardinals vs Fighting Irish Betting Odds, Trends & Analysis

Across their five previous road games, Louisville has an ATS mark of 1-4. Their straight up record in these matchups was 2-3 while averaging 21 points per game.
In their last five home games, Notre Dame has averaged 37 points per game while allowing 21. The team's record in this stretch was 3-2 while going 3-2 vs. the spread.
In their last five games as the betting underdog, the Louisville Cardinals have a straight up record of 2-3 and an ATS mark of 2-3.
Going back to their previous ten games as the favorite, Notre Dame has an ATS mark of 6-4 while going 7-3 straight up.